Emergency icon Important Updates

Silvia Perez Protto, MD, MS, MBA

Silvia Perez Protto, MD, MS, MBA
  • No ratings
  • 0 Patient Satisfaction Ratings
  • 0 Patient Comments
Title Medical director, End of Life Center
Department Intensive Care and Resuscitation
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Spanish
Surgeon No


Is Cleveland Clinic Part of Your Insurance?

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

View All Plans

About Silvia Perez Protto, MD, MS, MBA

Dr. Silvia Perez-Protto is a staff at the Intensive Care and Resuscitation Department at the Anesthesiology Institute at Cleveland Clinic, and Associate Professor of Anesthesiology at the Cleveland Clinic Learner College of Medicine. She is the medical director of the End of Life Center at the Office of Safety, Quality and Patient Experience.

Dr. Perez-Protto earned her medical degree and post-graduate intensive care medicine degree from Universidad de la Republica, Montevideo-Uruguay. She worked as an intensivist and transplant coordinator, conducting more than 100 organ donation interviews before relocating to the US in 2006. She earned the ECFMG certificate and completed her post-graduate training including anesthesiology residency and critical care fellowship at the Cleveland Clinic.

Dr. Perez-Protto is a fellow of the American College of Critical Care Medicine, and is the president-elect of the Women Professional Staff Association at the Cleveland Clinic.

Dr. Perez-Protto has published multiple research articles in peer-reviewed journals, as well as having contributed abstracts and presentations at a number of professional association meetings. She served on the Cleveland Clinic Bioethics Committee for 5 years.

Dr. Perez-Protto has developed the Advance Care Planning program at the Cleveland Clinic, with the goal of delivering goal-concordant care. She has led the implementation of “The Pause” to honor the person who dies at the hospital and the care provided by the team. She has co-created Death over Dinner for Healthcare https://deathoverdinnerhealthcare.org/ and "The Pause" App https://apps.apple.com/us/app/the-pause-app/id1482649724 to foster caregiver resilience related to end of life care.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Graduate School - Baldwin Wallace University
Healthcare Management
Berea, OH USA

Graduate School - Drexel University
Philadelphia, PA USA

Fellowship - Cleveland Clinic
Critical Care Anesthesiology
Cleveland, OH USA

Residency - Cleveland Clinic
Cleveland, OH USA

Residency - Cleveland Clinic
Pre-Resident Anesthesiology Non ACGME
Cleveland, OH

Fellowship - Cleveland Clinic
Clinical Research Fellow
Cleveland, OH

Residency - Hospital de Clinicas
Critical Care Medicine
Montevideo, Uruguay

Medical Education - Universidad de la Republica Montevideo Facultad de Medicina
Montevideo, Uruguay

Additional Training

  • Master of Science - Drexel University
    Master of Business Administration - Baldwin Wallace University


  • Anesthesiology
  • Anesthesiology - Critical Care Medicine

Specialty Interests

Critical Care Medicine. Advance Directives. Advance Care Planning. End of life care. Healthcare communication. Organ donor management

Research & Publications

Research & Publications

See publications for Silvia Perez Protto, MD, MS, MBA.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/15/2024, Dr. Perez Protto has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Back to Top