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Department Pulmonary Medicine
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Locations
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Appointment:
216.444.6503
Desk:
216.444.7655
Fax:
216.636.5384

Additional Locations

Specialties & Treatments

Specialty in Diseases & Conditions

  • Bronchiolitis Obliterans
  • Connective Tissue Diseases
  • Hypersensitivity Pneumonitis
  • Idiopathic Pulmonary Fibrosis
  • Interstitial Lung Disease (ILD)
  • Lung Dominant Connective Tissue Disease
  • Radiation Fibrosis - Lung
  • Rheumatic Lung Disease
  • Sarcoidosis
View all 9 Specialties +
Insurance

Insurance

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Biography

About Brian Southern, MD

Dr. Southern is a Staff Physician in the Respiratory Institute and Assistant Professor of Molecular Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. He has a secondary appointment as an Associate Staff Scientist in the Lerner Research Institute Department of Pathobiology, where his research focus is Idiopathic Pulmonary Fibrosis (IPF). Dr. Southern explores how fibroblasts and myofibroblasts (the scar-producing cells in IPF) interact with lung tissue matrix to propagate fibrosis. He has identified that the molecular motor protein, non-muscle myosin II, is a critical molecule driving fibrosis, and is further characterizing the myosin II pathway in fibroblasts in order to identify novel targets to halt fibrosis in patients with IPF.

In addition to his research activities, Dr. Southern conducts an outpatient clinic where he cares for patients with interstitial lung disease and sarcoidosis, and he is a co-investigator on a number of clinical trials for patients with IPF. He serves as the physician leader for the Cleveland area Pulmonary Fibrosis Support Group. He is also very active in social media (Facebook: https://www.facebook.com/idiopathicPF/; Twitter: @TodayIPF) where he provides the latest research, treatment options, and news for patients with IPF and their families.

Education & Professional Highlights

Education & Professional Highlights

Appointed
2012

Education & Fellowships

Fellowship - Case Western Reserve University - University Hospitals of Cleveland
Pulmonary & Critical Care Medicine
Cleveland, OH USA
2012

Residency - Case Western Reserve University - University Hospitals of Cleveland
Internal Medicine
Cleveland, OH USA
2009

Medical Education - University of Alabama School of Medicine
Birmingham, AL USA
2003

Undergraduate - University of Alabama at Birmingham
Birmingham, AL USA
1996

Professional Highlights

  • Dr. Southern has been invited to present his research findings at local and national meetings, including the American Thoracic Society International Conference, the Keystone Symposium on Fibrosis,and the Society for Clinical Research/Midwestern Section American Federation for Medical Research (CSCR/MWAFMR).  He has been awarded research funding from the National Institutes of Health (NIH), the Parker B Francis Foundation, Genentech, Inc., and the Cleveland Clinic Research Program Committee.  He has served as a grant reviewer for the Department of Defense Congressionally Directed Medical Research Programs (CDMRP), the Foundation for Sarcoidosis Research, and the Cleveland Clinic Research Program Committee. He reviews manuscripts for a number of scientific journals. He also supervises pulmonary fellows in the Interstitial Lung Disease Clinic and on the inpatient pulmonary consult service. Additionally, he serves as a volunteer physician at the Free Medical Clinic of Greater Cleveland. 

Certifications

  • Internal Medicine - Pulmonary Disease
  • Internal Medicine - Critical Care Medicine

Specialty Interests

Idiopathic Pulmonary Fibrosis, Interstitial Lung Diseases, Sarcoidosis

Awards & Honors

  • 2017 NIH K08 Award
  • 2017 Parker B Francis Fellowship Award (declined)
  • 2017 Parker B Francis Research Opportunity Award
  • 2015 Pulmonary Fibrosis Foundation Summit, Top Ten Abstract
  • 2015 Genentech Idiopathic Pulmonary Fibrosis Junior Faculty Award
  • 2014 Cleveland Clinic Research Program Committees Award
  • 2012 Travel Award, ATS Assembly on Respiratory Cell and Molecular Biology
  • 2009 The Peter Morgan Award, for outstanding leadership as a senior resident

Memberships

  • American Thoracic Society
  • American Society for Matrix Biology
  • American Association for the Advancement of Science
Research & Publications

Research & Publications

See publications for Brian Southern, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 2/28/2022, Dr. Southern has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

66 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

19 Patient Comments

Reviewed on Aug 25, 2022

We love Dr. Southern and we are so grateful to have access to "pick his brain" from afar. With progressing IPF, travel is no longer an option. The tech side of Cleveland Clinic's website always works so easily, love it!

Reviewed on Jun 17, 2022

The Dr was excellent, total good skills. Intelligent, Empathetic, Great communication, Understanding.

Reviewed on May 13, 2022

Dr. Brian Southern is in a class all by himself - he never deviated from his stated primary purpose, which was to provide me with the medical health care, delivering it big-time with a sense of warmth, friendliness, kindness, consideration, compassion and empathy, even going so far as to provide me with his cell phone number, reiterating time and again that all he wanted to do was help me - I was, literally, brought to tears by Dr. Southern's humility - he was unpretentious and unassuming but I was not fooled as I knew that my life was in the hands of one of the best pulmonary doctors in the country, if not in the world. The day that God put Dr. Southern in my life was the day I was blessed with an angel of the first degree who gave me something priceless - hope! To say that it was a pleasure to have made Dr. Southern's acquaintance would be the understatement of the millennium - what a prince he is!

Reviewed on May 6, 2022

Dr. Southern treats me like a family member. He is compassionate , listens, understands & comes up with possible treatments for my condition. EXCELLENT!!!

Reviewed on May 6, 2022

Dr. Southern is very caring. He makes the patient feel like they are important. He does not rush through the visit. He listens and discusses any and all concerns.

Reviewed on Apr 8, 2022

He is an excellent doctor.

Reviewed on Mar 10, 2022

Great doctor. Great staff

Reviewed on Mar 10, 2022

Dr Southern has always been right on top of my care. I'm Challenging and he's the best.

Reviewed on Feb 11, 2022

Excellent overall experience at the Cleveland Clinic. Dr. Brian Southern was excellent. He took the time to patiently listen and then explained in detail my reports, additional tests, and treatment options. Very impressed with the overall care and medical skill of the staff.

Reviewed on Jan 21, 2022

Would recommend Dr.Southern to anyone in need.

Reviewed on Jan 7, 2022

Dr.Southern is phenomenal. He has always listened closely to concerns and has referred me to many other excellent practitioners at Cleveland Clinic. I tell everyone I know about him. I'm a disabled nurse and medical instructor.

Reviewed on Dec 17, 2021

I was very happy to get an appointment so quickly. I've been hospitalized twice in the last 4.5 years and have met with a few pulmonologists (4). I feel relieved that Dr. Southern has been able to diagnose my lung issues. He referred me to Dr. Khabbaza (appointment in February) as he has expertise with my condition. I know that Dr. Southern spent a lot of time reviewing my situation/tests and I finally feel confident that I'm on the right track.Dr. Southern is wonderful and I highly recommend him. I look forward to being able to take care of myself and to feel better.

Reviewed on Dec 10, 2021

Dr. Southern and his staff is second to none. We received a diagnosis first visit. He made us feel at ease right away, great listener, and communicator. Thank you seems so inadequate.

Reviewed on Nov 26, 2021

I would refer anyone to Dr. Southern that would be appropriate.

Reviewed on Nov 26, 2021

One of the best doctors I have ever gone to!!

Reviewed on Nov 19, 2021

Dr Southern is excellent. He explains my condition and questions. He takes time with me. He is the best. And pulmonary function staff along with scheduling were excellent.

Reviewed on Oct 8, 2021

Dr Southern is knowledgeable yet humble and he always allows me to assist in my treatment. He is an excellent Doctor!!

Reviewed on Sep 24, 2021

I felt valued as a patient by Dr Southern returning after leaving for the day.

Reviewed on Sep 10, 2021

Dr. Southern was wonderful! He had no problem with me doing FaceTime with my son during the consultation. We liked the way he explained the progression of Sjorgren's in my lungs while showing us the CT. He spent a great deal of time with us and answered our questions.

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