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Department Cardiovascular Medicine
Primary Location Hillcrest Medical Building 2
Type of Doctor Adults Only
Languages English
Surgeon No
Hillcrest Medical Building 2
Primary Location

Hillcrest Medical Building 2

Specialties & Treatments

Treatment & Services

  • Abnormal Stress Test
  • Cardiac Catheterization
  • Cardiovascular Medicine Department
  • Catheterization (and Pre-Cath Exam)
  • Coronary Artery Atherectomy
  • Coronary Artery Stenting
  • Coronary Balloon Angioplasty (PTCA)
  • Electrocardiograph Tests
  • General Cardiology
  • Preventive Cardiology
  • Regional Heart and Vascular
  • Stress Testing
View all 12 Treatment & Services +

Specialty in Diseases & Conditions

  • Cardiovascular Disease
  • Coronary Aneurysm
  • Coronary Artery Disease
  • Heart Attack
  • Heart Disease
  • Heart Failure
  • Heart Murmur
  • Heart Palpitations
  • Heart Related Illnesses
  • Heart Valve Disease
  • High Blood Pressure (Hypertension)
  • High Cholesterol
  • Ischemic Cardiomyopathy
  • Mitral Valve Prolapse
  • Mitral Valve Regurgitation
  • Mitral Valve Stenosis
  • Pericardial Effusion
  • Pericarditis
  • Restenosis
  • Restrictive Cardiomyopathy
  • Rheumatic Heart Disease
View all 21 Specialties +


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About Jonathan Scharfstein, MD

Jonathan S. Scharfstein, MD, FACC, is a staff physician in the Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute and practices at Hillcrest Hospital with office in the Hillcrest Medical Building. Dr. Scharfstein is Chief of the Division of Cardiology, Medical Director of the Coronary Care Unit and has been the Medical Director of the Chest Pain Center since 2007 at Hillcrest Hospital. He is board-certified in internal medicine, cardiovascular disease and interventional cardiology.

Prior to his appointment to the Cleveland Clinic staff, Dr. Scharfstein was in private practice with Cardiovascular Associates of Cleveland. He has been on the medical staff at Hillcrest since 2000. His previous positions include appointments at Brigham and Women’s and University Hospitals in Boston, MA, Director of Interventional Cardiology and the cardiology fellowship training program at The Mt. Sinai Medical Center, Cleveland, and Co-Director of the cardiology fellowship training program at University Hospitals of Cleveland.

Specialty Interests: Coronary artery disease, angina, heart valve disease, hyperlipidemia, chest pain, heart catheterization, coronary angioplasty, coronary stenting

Number of Procedures Performed: Dr. Scharfstein has performed more than 6,000 heart catheterizations and 2,000 coronary interventions throughout his career.

Success Rates: Cleveland Clinic is nationally and internationally renowned for the world’s best cardiovascular care. Success rates for specific procedures are available at: https://my.clevelandclinic.org/departments/heart/about/outcomes-stats

Education and Training: Dr. Scharfstein earned his undergraduate degree from Princeton University and his medical degree from the University of Pennsylvania School of Medicine. He served an internship and residency in medicine at The Johns Hopkins Hospital, Baltimore, MD. He completed fellowships in clinical cardiology and interventional cardiology at Brigham and Women’s Hospital, Boston, MA, a research fellowship in medicine at Harvard University, Cambridge, MA, and a second fellowship in interventional cardiology at University Hospital, Boston.

In addition to his research fellowship at Harvard, which included teaching responsibilities, Dr. Scharfstein’s academic appointments have included clinical instructor positions at Harvard Medical School and Boston University School of Medicine. He has been an Assistant Professor of Medicine at Case Western Reserve University School of Medicine in Cleveland since 1995.

Research, Publications and Speaking: Dr. Scharfstein has been an investigator on a number of significant clinical trials related to interventional strategies for heart attack, and has published more than a dozen original papers, reviews and abstracts in professional journals.

About Dr. Scharfstein: “I enjoy cardiology because of the diversity of diseases in the field, all with their unique acute and chronic challenges.  I also enjoy meeting patients for the first time in the midst of an acute illness, such as a heart attack, providing them emergency care, getting them through their initial crisis, and then providing follow-up care over long periods of time.”

Leisure time activities: In his leisure time, Dr. Scharfstein enjoys golfing, travel, exercise and spending time with his family

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Boston Medical Center
Interventional Cardiology
Boston, MA USA

Fellowship - Brigham & Women's Hospital
Cardiovascular Disease
Boston, MA USA

Residency - Johns Hopkins Hospital
Internal Medicine
Baltimore, MD USA

Medical Education - University of Pennsylvania School of Medicine
Philadelphia, PA USA

Undergraduate - Princeton University
Princeton, NJ USA


  • Internal Medicine - Interventional Cardiology
  • Internal Medicine - Cardiovascular Disease

Specialty Interests

Coronary artery disease, heart catheterization, percutaneous coronary intervention, coronary angioplasty, coronary stenting, angina, heart valve disease, hyperlipidemia, chest pain.

Awards & Honors

  • 2009 – present, Best Doctors in America
Research & Publications

Research & Publications

See publications for Jonathan Scharfstein, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/5/2023, Dr. Scharfstein has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

397 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.8
Listens 5
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

32 Patient Comments

Reviewed on Feb 27, 2024

I really liked Dr.Scarfstein. Just making an appointment was the hardest. It took 4 months to make the appointment.

Reviewed on Feb 27, 2024

Long standing great doctor, patient relationship!

Reviewed on Feb 13, 2024

Dr. Sharfstein provides an abundance of information, has great communication and made sure I understood everything we discussed

Reviewed on Jan 26, 2024

Nothing but good experiences Dr. Scharfstein saved my life! Totally trust the doctor to manage my heart health!

Reviewed on Jan 26, 2024

I would highly recommend Dr. Scharfstein as a cardiologist.

Reviewed on Jan 16, 2024

This comment relates to all my Clinic doctors, not just this practice: When I schedule a 6 month follow up appointment while I'm there it works well. However if you need an appointment sooner it can be difficult to get one less than several months out. Difficult to reach some doctors offices directly without going through the appointment center

Reviewed on Dec 8, 2023

The doctor is excellent

Reviewed on Dec 1, 2023

He is the best. Very grateful to have him as my doctor!

Reviewed on Dec 1, 2023

Doctor very good, listens and explains very well.

Reviewed on Nov 28, 2023

Dr. Scharfstein and his team are completely attuned to the well being of the patients. Kind, courteous, respectful....

Reviewed on Nov 28, 2023

My wife and I felt very comfortable during the providers' visit.

Reviewed on Nov 17, 2023

Dr. Scharfstein remembered when I first had my heart attack. I'm so glad to have him on my current hospitalization.

Reviewed on Oct 27, 2023

Excellent physician. (And I am a physician, so I really know)

Reviewed on Oct 24, 2023

Dr Scharpstien is always a total professional an excellent communicator and always interested and and engaging in conversation

Reviewed on Oct 24, 2023

Dr. Scharfstein listens and explainsEverything.

Reviewed on Sep 26, 2023

Dr. Scharfstein is fabulous.

Reviewed on Sep 20, 2023

Dr. Scharfstein is a brilliant and caring physician..

Reviewed on Sep 19, 2023

Dr Scharfstein was direct.and inspired a great deal of confidence and competence

Reviewed on Aug 18, 2023

The Dr. Was timely, considerate, showed interest in my condition, examined an issue, looked at prior matters, consolidated with a college and gave me the conclusions as desired.

Reviewed on Jul 26, 2023

This follow up appointment was so important to me and Dr. Scharfstein was generous with his time and explanations and support.

Reviewed on Jul 25, 2023

My visit with the doctor was timely and professional

Reviewed on Jul 21, 2023

Very good experience very professional very good doctor

Reviewed on Jul 21, 2023

My doctor Sharpstein does a good job

Reviewed on Jun 16, 2023

Rather cold and indifferent to me. Seemed to be on a tight schedule so doctor seemed in a hurry to finish my visit

Reviewed on Jun 9, 2023

Dr. Scharfstein is fabulous!

Reviewed on Jun 9, 2023

I would recommend Dr. Scharfstein to anyone who needs an excellent cardiologist.

Reviewed on Jun 9, 2023

Dr Scharfstein is the Best!

Reviewed on May 19, 2023

Excellent Physician

Reviewed on Apr 21, 2023

Dr. Scharfstein is an excellent physician. Aside from being an expert in his field, it is obvious to me that he truly cares about his patients. He is an outstanding professional.

Reviewed on Apr 21, 2023

Dr. Scharfstein was very personable and easy to talk to. He listen to my concerns and addressed completely.

Reviewed on Apr 18, 2023

Dr Scarfstien is outstanding

Reviewed on Apr 14, 2023

Dr. Scharfstein is outstanding and he genuinely cares about his patients. Also, extremely professional and practical in his advice.

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