alert icon Coronavirus
Now scheduling COVID-19 appointments
Learn About Vaccine Availability
COVID-19 Vaccine FAQs
New Visitation Hours
COVID-19 Testing Information
Department Allergy and Clinical Immunology
Primary Location Avon - Richard E. Jacobs Health Center
Type of Doctor Both Adults and Children & Adolescents
Languages English, Spanish
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Allergy Immunotherapy
  • Allergy Skin Tests
  • Allergy Tests
  • Blood Tests
  • Diagnosing Asthma
  • Diagnostic Skin Testing For Food, Inhalant, And Drug Allergy
  • Exhaled Breath Analysis
  • Immunodeficiency Evaluation
  • Immunoglobulin Infusion
  • Immunotherapy
  • Peak Flow Meter
  • Pulmonary Function Testing
  • Screening and Testing
  • Treating Asthma With Bronchodilators
View all 14 Treatment & Services +

Specialty in Diseases & Conditions

  • Airborne Allergens
  • Allergic Conjunctivitis
  • Allergic Disorders
  • Allergies
  • Allergy Skin Testing
  • Anaphylaxis
  • Asthma
  • Asthma Causes & Triggers
  • Bee Stings
  • Eczema
  • Egg Allergy
  • Environmental Allergies
  • Eosinophilia
  • Fish Allergy
  • Food Allergies
  • Hay Fever
  • Hives (Urticaria)
  • Insect Sting Allergies
  • Latex Allergy
  • Mastocytosis
  • Medication Allergies
  • Milk Allergies
  • Milk Allergy
  • Nut Allergy
  • Ocular Allergies
  • Primary Immunodeficiencies
  • Primary Immunodeficiency Disease
  • Seasonal Allergies
  • Shellfish Allergy
  • Soy Allergy
  • Urticaria
  • Wheat Allergy
View all 32 Specialties +


Is Cleveland Clinic Part of Your Insurance?

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

View All Plans
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Allergy Immunology
Cleveland, OH USA

Residency - Northwestern University, Foster McGaw Medical Center
Internal Medicine
Chicago, IL USA

Medical Education - Michigan State University College of Human Medicine
East Lansing, MI USA

Undergraduate - Michigan State University
East Lansing, MI USA


  • Internal Medicine
  • Allergy and Immunology

Specialty Interests

Allergic rhinitis, sinusitis, asthma, venom allergy, hives

Research & Publications

Research & Publications

See publications for Roxana Siles, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 2/16/2021, Dr. Siles has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Donation of Financial Interest. Dr. Siles has consulted for, received compensation for serving as a fiduciary from, or received royalties from the following companies but instructed them to donate all compensation to not-for-profit causes or to the Cleveland Clinic to support research and education:

  • American College of Allergy, Asthma and Immunology

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

178 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

60 Patient Comments

Reviewed on Jan 26, 2021

Dr. Siles was very professional and knowledgeable about my allergy issues. Her level of detail was very comforting. She went above and beyond by quickly responding to messages I sent in MyChart.

Reviewed on Jan 25, 2021

The Dr. explained very clearly all the options for treatments. I will definitely recommend her. She has helped me tremendously.

Reviewed on Dec 31, 2020

Dr. Siles is wonderful! Very helpful and informative AND very nice and easy to talk to.I would definitely recommend her!

Reviewed on Dec 14, 2020

Had all my questions and concerns addressed. Dr and her staff were very good on updating during all procedures

Reviewed on Dec 9, 2020

excellent dr.

Reviewed on Nov 24, 2020

Dr. Stiles was wonderful. she took time, truly listened and made sure my treatment plan met my needs. she went above and beyond helping figuring out a problem with one of my medications. She is thorough, kind, caring and feel very fortunate to have her as my doctor.

Reviewed on Nov 11, 2020

She is honestly the best doctor I've ever had. And the staff is so friendly and helpful.

Reviewed on Nov 4, 2020

I felt very well-informed when she gave me the opportunity to call my provider to make sure my treatment would be covered

Reviewed on Oct 20, 2020

Dr Siles is awesome. She is very attentive, thorough in her explanations and very personable. highly recommend.

Reviewed on Oct 19, 2020

Dr. Siles is caring, empathetic, relates to my issues and needs... she is compassionate and is always a pleasure to see her. Her demeanor makes her an even better professional, as she shows true interest in my concerns.

Reviewed on Oct 14, 2020

the doctor is terrificone of the best I have ever had help me with my care.

Reviewed on Oct 13, 2020

Dr. Roxana Siles is Very good And nice Doctor . she is my daughter's favorite Doctor And nurse Lisa is Very good nurse also

Reviewed on Oct 8, 2020

Getting information is wonderful of contacting the doctor through mychart. If it is important during the day then I would call.

Reviewed on Oct 8, 2020

It's nice to go for to the doctors and you are not sick

Reviewed on Oct 1, 2020

Dr. Siles seemed to care

Reviewed on Sep 22, 2020

Dr Roxanna Stiles is an excellent doctor. she is very caring and gave me great advice for all of my concerns.

Reviewed on Sep 22, 2020

I have strongly recommended Dr Roxanna Stiles to others. She is very Professional and has a wonderful bedside manner.

Reviewed on Sep 14, 2020

Dr Siles really listens. She talks "with" me instead of "at" me like has been my experience with other clinic doctors.

Reviewed on Sep 14, 2020

Dr. Siles pays attention to me as a person and listens to my concerns, so I feel as though I'm receiving better care.

Reviewed on Aug 27, 2020

dr Siles is always very thorough and very prepared. I find it therapeutic when I get to spend time with her. I know I am in good hands in her care.

Reviewed on Aug 14, 2020

I am VERY happy with Dr. Siles.

Reviewed on Aug 13, 2020

I would recommend Dr. Siles to everyone struggling with allergies of any kind

Reviewed on Jul 28, 2020

Dr. Siles is very good! She takes her time doesn't rush you and explains things very well

Reviewed on Jul 17, 2020

The physician was not able to join the appointment on her end so we did an over the phone appointment. which was just fine

Reviewed on Jul 10, 2020

First time face to face. Dr was very professional, patient, and listened to my concerns. I would recommend Dr Siles to anyone with allergy issues

Reviewed on Jul 7, 2020

Excellent Doctor. She listens to you and never hurries you.She was able to diagnose me when no other doctor could.

Reviewed on Jul 6, 2020

Dr. Siles is one of my favorite physicians. A thorough,caring and thoughtful doctor.

Reviewed on Jul 6, 2020

Nothing can completely replace the nuances of in person visits. However,virtual visits are extremely important during the pandemic, as well for those unable to physically get to a doctor. Virtual visits are a great asset!

Reviewed on Jul 2, 2020

Dr. Siles is also professional, Friendly, knowledgeable and helpful in any way possible. Wonderful caring Dr.

Reviewed on Jun 29, 2020

Dr. Siles saved my life! My allergies and asthma were getting worse and I had problems when I was outside. I had a lot of trouble breathing during peak allergy periods and often took OTC allergy pills twice or three times a day. I missed annual Memorial Day picnics and graduation parties. Then 2 years ago, Dr. Siles suggested Xolair injections and explained the risks. I trust Dr. Siles so I tried it. Now, my asthma flare-ups are few and far between. I cannot imagine how high my risk factors would have been during the COVID-19 pandemic if Dr. Siles had not helped me get my allergies and asthma under control. Thank you!

Reviewed on Jun 23, 2020

my best experience with the Cleveland Clinic has been with Dr. Siiles. She explains everything with great clarity, shows how test results support her recommendations, and she is just the most pleasant person to spend time with. I never feel rushed, and all of her recommendations have made me feel so much better.

Reviewed on Jun 19, 2020

very informative physician.

Reviewed on Jun 16, 2020

Although a periodic, routine visit, Dr. Siles was thorough in reviewing my past history and updating me on the present implications of my condition. She answered questions thoroughly and on point. All of this came with an easy manner that provided me with a sense of both calm and authority.

Reviewed on Jun 12, 2020

Excellent experience with Dr. Siles

Reviewed on Jun 9, 2020

Dr. Siles Nurse Manager, Jill, made every effort to schedule all three appts consecutively so that I only had to make one trip in to the hospital for my safely.

Reviewed on Jun 9, 2020

Dr. Siles is the wonderful example of how The Cleveland Clinic advertises their responsibility for your care and wellness. She is so smart and so caring! I was treated for my medical problem for 9 yrs at another medical facility with minimal improvement. After coming to CC, within 4months of treatment, Dr. Siles had given me my life back. Over the next 12 months I did have a couple setbacks but Dr. Siles knew how to adjust my medications to remedy the problem making improvements each time. I owe my life to her! I have praised her many times to my friends and acquaintances and will continue to recommend her and your facility!

Reviewed on Jun 9, 2020

she is a "wonderful Doctor" Excellent!!

Reviewed on Jun 9, 2020

again. great Doctor !!

Reviewed on Jun 5, 2020

Dr. Siles is my favorite doctor. She is professional, knowledgeable, compassionate, understanding, respectful, and kind. I always know she cares about me as a person and is willing to do whatever she can to help me. I recommend her every time I get the chance.

Reviewed on Jun 4, 2020

Have loved all the tools and advice given to me each time I've worked with Dr Siles. She listens, she asks meaningful follow-up questions, she advises. Dr. Siles empowers.

Reviewed on May 28, 2020

Dr. Siles has always taken great care of me; she asks great questions regarding my needs and listens to my questions

Reviewed on May 19, 2020

This provider was excellent and very thorough to take a patient history. I would recommend her to friends and family.

Reviewed on May 18, 2020

Dr Siles was very thorough went over all my medication and asked questions about how well each was working for me and gave me instructions and support

Reviewed on May 18, 2020

I would prefer to see the doctor in person, but under the circumstances this worked well

Reviewed on May 12, 2020

Dr. Siles is amazing!

Reviewed on May 12, 2020

great video connection and very easy to talk to doctor

Reviewed on May 7, 2020

Dr. Siles provides excellent care. She is very thorough and always provides clear explanations. I enjoy talking with her.

Reviewed on May 5, 2020

I like how doctors are trying to help their patients, even if they have to do it in a different way.

Reviewed on Apr 27, 2020

Dr Siles takes the time to listen to the patient. I believe she truly has my best interest in mind with her approach to my care.

Reviewed on Apr 16, 2020


Reviewed on Apr 14, 2020

Dr Siles office contacted us to arrange. it was an easy process.

Reviewed on Apr 14, 2020

I have recommended Dr Siles to others. she has a way about explaining that's easy to understand yet thorough. She included my child in the plan and made sure he understood.

Reviewed on Apr 13, 2020

I enjoyed the virtual visit I had with Dr Siles

Reviewed on Mar 10, 2020

Dr Siles ,is the best , she listens and cares .

Reviewed on Mar 10, 2020

one of the more caring doctors at the Cleveland clinic

Reviewed on Feb 27, 2020

Dr. Siles and her assigned clinic have always provided me with great service!

Reviewed on Feb 27, 2020

I have seen Dr Siles for a few years now, she is the first doc to stabilize my allergies, acid reflex and asthma. I have had a chronic cough for years, I am now stabilized on a good regimen of meds and have not had to go a prednisone for at least 12-16 months. She spent a lot of time with me gathering my symptoms and in addition to being stabilized on meds has told me I no longer meet the criteria for having asthma, good to be off that med

Reviewed on Feb 27, 2020

Highly recommend CCF and this doc and clinic!

Reviewed on Feb 21, 2020

I found Dr. Siles to be a wonderful healthcare provider.

Reviewed on Feb 21, 2020

I have had 3 allergists, due to business relocations. Dr. Stiles is far & away the best doctor I have had -- she essentially resolved my severe allergy with the right medications, provided some excellent lifestyle tips to accommodate the allergy, and even noted the interaction with another medical condition that no other doctor had caught. I can't recommend her highly enough, and I'm very grateful that she is my doctor.

Related Videos Featuring Roxana Siles, MD

Related Videos Featuring Roxana Siles, MD

Back to Top