About Digestive Disease Institute

Welcome to the Cleveland Clinic Digestive Disease Institute (DDI). We offer patients the most advanced, safest and proven medical and surgical treatments primarily focused on disorders related to the gastrointestinal tract.

Of the top digestive disease centers in the United States, DDI is the first of its kind to unite all specialists in gastroenterology and hepatology, bariatric surgery, colorectal surgery, hepato-pancreato-biliary and transplant surgery, and nutrition within one unique, fully integrated model of care – aimed at optimizing the patient experience.

This exciting model of care also helps us offer effective and patient-friendly service, including shorter waits for appointments and more seamless interaction with all of our specialists. In addition, our institute model enhances opportunities for cutting-edge research and physician education.

Watch Video: Digestive Disease Institute Overview

The Digestive Disease Institute has been ranked second in the nation by U.S.News & World Report’s Best Hospitals Survey since 2003, and first in Ohio since 1990.

Institute Mission Statement

The mission of Cleveland Clinic Digestive Disease Institute is to foster the most effective, efficient and compassionate multidisciplinary digestive health care through innovation: ‘Devise, Optimize, Economize without Compromise’.

Digestive Disease 2013 Outcomes

We focus on reconnecting quality and patient safety with clinical care. This collaboration supports the Cleveland Clinic health system’s commitment to quality and patient care, which parallels major healthcare initiatives nationwide.

Download a copy of our 2013 Outcomes.

News Archives



Researchers find liver stiffness is strongly associated with steatosis and diabetes. Dr. Naim Alkhouri shares his perspective.
Co-infection of hepatitis B and hepatitis C significantly increases your risk of liver damage. Dr. Ibrahim Hanouneh comments.


Experts discuss the nutritional benefits of eating salmon. Registered dietitian Julia Zumpano comments.
Television special highlights the importance of organ donation and transplantation. Dr. John Fung, Dr. Charles Miller, and Cleveland Clinic patient are featured.
Registered dietitian Laura Jeffers discusses the most common mistakes people make when dieting


Nutrition experts discuss whether pretzels are a healthy snack. Registered dietitian Kate Patton comments.
Registered dietitian Laura Jeffers gives examples of hydrating foods you can eat during hot weather.
Nutrition experts offer both pros and cons of drinking butter coffee. Registered dietitian Laura Jeffers comments.
Tribute honors the late Dr. Victor Fazio. Dr. James Church comments.
Patient shares wedding dance with her physician, Dr. John Fung, 10 years after life-saving liver transplant.
Dr. John Fung, director of the Cleveland Clinic Health System Transplantation Center, discusses pediatric liver transplant rejections.
Experts discuss 10 essential facts about hepatitis C. Dr. Ibrahim Hanouneh comments.
New study finds moderate amounts of any type of alcohol may offer cardioprotective benefits. Registered dietitian Julia Zumpano comments.
Woman with rare disease continues to hope for a cure. Dr. Matthew Kroh is mentioned.
Experts discuss whether or not burgers should be part of a healthy diet. Registered dietitian Julia Zumpano comments.
Woman with rare disease continues to hope for a cure. Dr. Matthew Kroh comments.
Registered dietitian Julia Zumpano shares tips for a healthy barbeque.
Registered dietitian Laura Jeffers talks about some of the health advantages you may gain by shopping at a farmers market.


Dr. John Fung recently attended the wedding of a patient who received a life-saving liver transplant eleven years ago.
Dr. Aaron Brzezinski discusses medications to keep Crohn’s disease in remission.
Registered dietitian Laura Jeffers talks about some of the most nutritious vegetables you can work into your diet.
Experts debate whether butter should be a part of a healthy diet. Registered dietitian Julia Zumpano comments.
Patient with rare disease is seeing progress in her health while under the care of Dr. Matthew Kroh.
A new study suggests eating up to two chocolate bars a day can lower your risk of heart disease. Registered dietitian Kate Patton comments.
A new study finds people who are assigned a diet adhere better and lose more weight than people who pick their own diet plan. Registered dietian Laura Jeffers comments.
Dr. Maged Rizk shares things you can do to decrease the risk of constipation.
Researchers discover that people who drink just one or more sugar-sweetened beverage a day are at an increased risk of developing non-alcoholic fatty liver disease. Dr. William Carey comments.
Experts discuss the nutritional benefits of tilapia. Registered dietitian Julia Zumpano comments.
Dr. John Vargo comments on results of study presented at Digestive Disease Week 2015.


Dr. John Vargo shares his perspective on study results presented at Digestive Disease Week.
Dr. John Vargo comments on results of study presented at the Digestive Disease Week annual meeting.
Dr. Naim Alkhouri and researchers present results from recent study at the annual Digestive Disease Week meeting.
Dr. Jamile Wakim-Fleming discusses several new endoscope technologies.
Experts discuss whether pork is a good choice for your health. Registered dietitian Kate Patton comments.
A new study finds supplementing the heart-healthy Mediterranean Diet with olive oil or nuts may help protect the brain. Registered dietitian Julia Zumpano comments.
Dr. Ibrahim Hanouneh explains how hepatitis C treatment has changed.
Woman shares how rare disorder has affected her life. Dr. Matthew Kroh comments.


Experts suggest avoiding fat-free half and half. Registered dietitian Julia Zumpano comments.
Experts suggest avoiding fat-free half and half. Registered dietitian Julia Zumpano comments.
The Undy Run/Walk for colon cancer awareness took place Saturday at Edgewater Park.
The Undy Run/Walk for colon cancer awareness takes place this Saturday at Edgewater Park. Dr. Matthew Kalady comments.
Registered dietitian Kate Patton shares tips for a healthier Easter dinner.
Experts discuss whether smoothies are beneficial to your diet. Registered dietitian Laura Jeffers comments.
Dr. Ryan Williams answers questions about colon cancer.


Registered dietitian Kate Patton explains the health benefits of eliminating meat from your meals every Monday.
"Semicolon; The Adventures of Ostomy Girl," will have two screenings this week at the Cleveland International Film Festival
Dr. Emina Huang busts common myths about colon cancer and colonoscopies
A new study finds a diet dominated by fruits and vegetables, but also containing a moderate amount of fish, could cut your risk for colorectal cancers by nearly 45 percent.

Cleveland Clinic physician Dr. Ryan Williams comments.

Dr. Feza Remzi was awarded the Cleveland Champions Award

The award recognizes an individual for his or her effort to bring meetings and conventions to Cleveland.

Julia Zumpano, registered dietitian, comments on the Mediterranean diet
Dr. Carlos Romero-Marrero provides information on signs and symptoms of colon cancer.
Dr. Maged Rizk, gastroenterologist, discusses the latest health fad, charcoal juice
Dr. Emina Huang discuss the importance of colonoscopies in preventing colon cancer
Study finds big breakfasts and small dinners might be a healthier way to eat for people with type 2 diabetes

Registered dietitian Anna Taylor Comments

Experts warn against coconut products for heart patients

Registered dietitian Kate Patton comments


Dr. Carlos Romero-Marrero discusses the new Hispanic Clinic at Lutheran Hospital
Registered dietitian Kate Patton explains the difference between good carbohydrates and bad carbohydrates
Dr. Marc Gillinov and Julia Zumpano, RD, discuss the best foods to eat for a healthy heart
Registered dietitian Laura Jeffers comments on new policy statement regarding school nutrition

Final frontier for school nutrition: Bake sales

Registered dietitian Laura Jeffers discusses which fad diets are best and worst for your health
Registered dietitian Julia Zumpano explains the importance of fiber in a dietary plan

High fiber intake is one of the most important aspects of the AHA diet.

Registered dietitian Kate Patton shares heart healthy options for a Valentine’s Day dinne
Valentines meal options.
Cleveland Clinic will collaborate with CWRU and University Hospitals in research on digestive inflammation, gastrointestinal cancer and liver and metabolic diseases as part of a new grant received by CWRU

Digestive Diseases Research Core Center, one of only 17 in the country.

Woman with rare cancer undergoes long-awaited liver transplant at Cleveland Clinic

A major victory in her fight for life.

The FDA recently approved a drug to treat binge-eating disorder. Dr. Leslie Heinberg comments

Food and Drug Administration approved Vyvanse an effective option to help curb episodes of binge-eating.



Cleveland Clinic researchers develop online tool to predict colorectal cancer risk

Dr. Brian Wells and Michael Kattan, Ph.D., chair of the Department of Quantitative Health Sciences comments.

Dr. Matthew Kalady is monitoring a family with hereditary colon cancer

Family beats genetic condition.


Living liver donation saves child with a rare disease

Mom donates part of her liver to baby daughter.


Man donates part of his liver to save his friend

Patients treated at Cleveland Clinic.



12 Years Old With 'a 100 Percent Chance' Of Getting Cancer

Ansleigh Adkins was fast-tracked for surgery when doctors found her colon carpeted with polyps. She has a genetic disease called FAP, familial adenomatous polyposis, which makes colon cancer inevitable.


Bariatric & Metabolic Institute Director Dr. Philip Schauer discusses Gov. Chris Christie’s Lap-band Surgery
Cleveland Clinic's Digestive Disease Institute Receives $2 Million to Endow Chair in Colorectal Surgery

Kenneth M. Garschina and his wife, Sara Story, have pledged $2 million to Cleveland Clinic’s Digestive Disease Institute to create an endowed chair for research in colorectal surgery.


Crohn's disease surgery helps man now able to swim across Lake Erie

Dr. Meagan Costedio weights in on a colon removal surgery that helped Ryan Stevens get back his life.


Cleveland Clinic now performing fecal transplants for patients with stubborn cases of C. diff

Dr. John Fung, a transplant surgeon and chairman of the Clinic’s Digestive Disease Institute, comments on procedure.


Cleveland Clinic performs surgery to help 12-year-old with a 100 percent risk of colon cancer

Cleveland Clinic's Dr. Matthew Kalady comments on the girl's brave journey.


Colonoscopies are huge benefit for detecting colon cancer

Studies show the importance of colonoscopies as a screening tool for colon cancer. Dr. James Church and his patient are featured.


Cleveland Clinic annual event held at Global Center for Medical Innovation in downtown Cleveland

Cleveland Clinic’s 11th Annual Medical Innovation Summit will examine obesity, diabetes and the metabolic crisis. Dr. Philip Schauer comments.

Study finds diabetes patients with Barrett’s esophagus may face greater likelihood of esophageal cancer

Cleveland Clinic's Dr. Prashanthi Thota comments.


Experts discuss changes in the treatment of hepatitis C.

A big change is coming for hepatitis C. treatment. Cleveland Clinic's Dr. William Carey comments.

Schedule an Appointment Online

Call us for an Appointment

To find a digestive specialist for your needs, contact the Digestive Disease Institute at 216.444.7000 (or toll-free 1.800.223.2273, ext. 47000)

Same-day Appointments

To arrange a same-day visit, call 216.444.7000

This information is provided by Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition.

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