Autoimmunity and POTS: Implications in Diagnosis and Management

Dr. Albert Aboseif and Dr. Daniel Bireley, of Cleveland Clinic's Mellen Center for Multiple Sclerosis, discuss postural orthostatic tachycardia syndrome (POTS), including mechanisms that might contribute to the development of POTS and current immunotherapy research.

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Learning Objectives

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Provide physicians with up-to-date, practical clinical information relevant to internal medicine, cardiology, and related fields.
Relay clinical breakthroughs that are changing medical practice and advise listeners how to apply them in daily patient care.

Target Audience

The education is designed for primary care and internal medicine physicians, cardiologists, endocrinologists, and pulmonologists.

Accreditation

In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

American Medical Association (AMA)

Cleveland Clinic Center for Continuing Education designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Activity Director and Faculty

Activity Directors

Anthony Fernandez, MD, PhD
Director, Medical and Inpatient Dermatology
W.D. Steck Chair of Clinical Dermatology
Co-Director, Center for Continuing Education
Cleveland Clinic, Cleveland, OH

Steven Kawczak, PhD, CHCP, FACEHP
Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine of CWRU
Co-Director, Center for Continuing Education
Director, Center for International Medical Education
Staff, Center for Educational Resources
Education Institute
Cleveland Clinic, Cleveland, OH

Moderator

Andrei Brateanu, MD
Assistant Professor of Medicine, Case Western Reserve University
Senior Associate Program Director, Internal Medicine Residency Program, Medicine Institute
Cleveland Clinic, Cleveland, OH

Faculty

Albert Aboseif, DO
Mellen Center for Multiple Sclerosis, Neurological Institute
Cleveland Clinic, Cleveland, OH

Daniel Bireley, MD
Mellen Center for Multiple Sclerosis, Neurological Institute
Cleveland Clinic, Cleveland, OH

Faculty Disclosure

In accordance with the Standards for Integrity and Independence issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Center for Continuing Education mitigates all relevant conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they may have a relationship, which in the context of their presentation(s), could be perceived as a potential conflict of interest:

Anthony Fernandez, MD, PhD

Company	Relationship
Biogen, Boehringer Ingelheim, Bristol-Myers Squibb Co., UCB, Inc.	Consulting
Pfizer, Inc.	Other activities from which remuneration is received or expected awarded a grant to fund a medical dermatology fellowship position; Research: PI
Mallinckrodt Inc., Novartis	Consulting; Teaching and Speaking
Alexion	Research: Principal Investigator
Abbvie Pharmaceuticals	Consulting; Advisor or review panel participant; Teaching and Speaking
Kyowa Kirin	Teaching and Speaking
Company
Biogen, Boehringer Ingelheim, Bristol-Myers Squibb Co., UCB, Inc.
Relationship
Consulting
Pfizer, Inc.
Relationship
Other activities from which remuneration is received or expected awarded a grant to fund a medical dermatology fellowship position; Research: PI
Mallinckrodt Inc., Novartis
Relationship
Consulting; Teaching and Speaking
Alexion
Relationship
Research: Principal Investigator
Abbvie Pharmaceuticals
Relationship
Consulting; Advisor or review panel participant; Teaching and Speaking
Kyowa Kirin
Relationship
Teaching and Speaking

The following faculty have indicated they have no relationship which, in the context of their presentation(s), could be perceived as a potential conflict of interest: Albert Aboseif, DO, J. Daniel Bireley, MD, Andrei Brateanu, MD, Steven Kawczak, PhD

This CME activity was produced by The Cleveland Clinic Foundation Center for Continuing Education.

CME Disclaimer

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

HOW TO OBTAIN AMA PRA Category 1 Credits™ OR CERTIFICATE OF PARTICIPATION:

Click here to log into myCME and begin the activity evaluation and print your certificate. If you need assistance, contact the CME office at myCME@ccf.org