Skin grafting is a type of surgery. Providers take healthy skin from one part of the body and transplant (move) it. The healthy skin covers or replaces skin that is damaged or missing. Skin loss or damage can result from burns, injuries, disease or infection. Providers may recommend a skin graft after surgery to remove skin cancer.
Skin grafting is a type of surgery. During this procedure, providers take healthy skin from one part of the body and transplant (move) it to cover skin that’s damaged or missing. Within a few days, the grafted skin begins to develop blood vessels and connect to the skin around it.
Providers use skin graft surgery to help people who have damaged skin from burns, injuries, wounds, disease or infection. If you’ve had surgery to remove skin cancer, your provider may recommend a skin graft to cover the missing skin.
The recovery time after this surgery varies depending on your overall health, the size of the graft and the technique your provider used. Most skin graft procedures are successful the first time. Sometimes, the transplanted skin doesn’t heal well or “take” to the surrounding skin. If this happens, you may need another skin graft.
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Most often, providers use healthy skin from a person’s own body. They call this skin graft procedure an autograft.
Sometimes, there isn’t enough healthy skin on a person’s body to use for the procedure. If this happens, a provider may take the skin from a cadaver (allograft).
Providers can also use skin from an animal, most commonly a pig (xenograft). Allograft and xenograft skin grafts are usually temporary. They cover the damaged skin until the wound heals or the person grows enough healthy skin to use for a permanent skin graft.
The types of skin graft surgery are:
Your provider may recommend a skin graft if you have damaged or missing skin that cannot heal on its own. Skin grafts help people who have skin loss due to:
Before skin graft surgery, your provider may ask you to stop taking some medications (such as blood thinners). If you smoke, you should quit several weeks before surgery. People who smoke are more likely to have complications from a skin graft. Smoking makes it harder for your skin to heal after surgery.
You will visit your provider before surgery to plan the procedure and determine the location of the donor site. The donor site is the piece of healthy skin that your provider will remove. They will transplant the healthy skin to the graft site (the damaged or missing skin). When choosing which healthy skin to transplant, your provider will look for skin that matches the tone and texture of the graft site.
You will have skin graft surgery in a hospital. Usually, your surgery is done under general anesthesia (fully asleep), although smaller grafts can be done with local anesthesia. The surgeon will make incisions (cuts) and remove healthy skin from the donor site. Depending on the technique your provider uses, they may remove healthy skin from the:
Before transplanting the healthy skin, your provider may poke little holes in it or make several tiny crisscrossed cuts. Providers call this technique meshing. The healthy skin may look like a fishnet. This technique allows your provider to stretch the skin over a larger area. It also helps the area heal after surgery.
Your provider places the healthy skin over the damaged or missing skin. They secure the skin in place with stitches or staples and put a dressing over the area. The donor site and graft site will heal after surgery. But it will probably take more time for the graft site to heal.
A skin graft usually involves two surgical sites (the donor site and the graft site). Your provider will monitor your health, look for signs of infection and make sure both sites are healing properly.
After surgery, you may need to stay in the hospital for up to two weeks. The length of stay depends on the type of skin graft surgery you get. Follow your provider’s instructions when you go home from the hospital. They may ask you to:
Skin grafts can replace lost skin, improve the appearance of damaged skin and restore function. This surgery is an effective treatment for skin loss that results from many different conditions.
Most skin grafts are successful. But sometimes the transplanted skin doesn’t take to the new area. If the transplanted skin doesn’t take, you may need another skin graft. An unsuccessful skin graft usually results from:
Other complications of skin graft surgery include:
Recovery time after skin graft surgery depends on your overall health, the size and type of skin graft and the location of the graft site. Your provider may recommend waiting several weeks before exercising, driving or lifting anything heavy. Ask your provider when you can get back to the activities you enjoy.
Call your provider right away if you have:
Children who have skin graft surgery may need another procedure as they grow. Sometimes, the transplanted skin doesn’t grow and stretch along with the child’s skin. If your child has a skin graft, ask your provider about the need for future surgeries.
A note from Cleveland Clinic
Healthcare providers use skin grafting to help large wounds heal, replace lost skin and improve the appearance of damaged skin. Most skin graft surgeries are successful. But sometimes the donor skin doesn’t take to the graft site. If that happens, you may require another skin graft. To lower your risk of complications, follow your provider’s post-surgery instructions carefully. Before surgery, tell your provider about any medications you’re taking. If you smoke, talk to your provider about quitting smoking before surgery.
Last reviewed by a Cleveland Clinic medical professional on 07/21/2021.
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