Mitomycin for Pyelocalyceal Solution

What is this medication?

MITOMYCIN (mye toe MYE sin) is a chemotherapy drug. This medicine is used to treat cancer of the urinary tract.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): JELMYTO

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• a hole or tear in your bladder or urinary tract
• low blood counts, like white cells, platelets, or red blood cells
• swelling or narrowing of the tube that carries urine from the kidney to the bladder
• an unusual or allergic reaction to mitomycin, other medicines, foods, dyes or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medication?

This drug is given as a catheter infusion into the kidney. It is administered in a hospital or clinic by a specially trained health care provider. You will be given directions to follow before the treatment. Follow your health care provider's directions carefully.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medicine.

Do not let urine touch your skin for at least 6 hours after treatment. Males and females should sit on the toilet when urinating. Flush the toilet several times after you use it. Wash your hands, inner thighs, and genital area with soap and water each time after going to the bathroom. If urine gets on your clothing, wash it right away. Wash it separately from other clothing.

Do not become pregnant while taking this medicine or for 6 months after stopping it. Women should inform their health care professional if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is potential for serious side effects to an unborn child. Talk to your health care professional for more information.

Do not breast-feed an infant while taking this medicine and for 1 week after stopping it.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives; swelling of the face, lips, or tongue
• change in the amount of urine
• nausea, vomiting
• pain in the lower back or side
• red or dark brown urine
• signs and symptoms of infection like fever; chills; cough; sore throat; pain or trouble passing urine

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

• signs and symptoms of low red blood cells or anemia such as unusually weak or tired; feeling faint or lightheaded; falls; breathing problems
• stomach pain
• violet to blue color of the urine

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medicine is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.