Tralokinumab Injection

What is this medication?

TRALOKINUMAB (tral oh kin ue mab) reduces swelling, redness, and itching of the skin caused by eczema. It works by decreasing inflammation of the skin.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Adbry

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Eye disease
• Parasitic (helminth) infection
• Recent or upcoming vaccine
• Vision problems
• An unusual or allergic reaction to tralokinumab, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

This medication is injected under the skin. You will be taught how to prepare and give it. Take it as directed on the prescription label. Keep taking it unless your care team tells you to stop.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.

This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. Then continue your normal schedule. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. Call your care team with questions.

What may interact with this medication?

• Vaccines

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication.

This medication can decrease the response to a vaccine. If you need to get vaccinated, tell your care team if you have received this medication. Extra booster doses may be needed. Talk to your care team to see if a different vaccination schedule is needed.

Tell you care team right away if you have any change in your eyesight or have eye pain.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions or angioedema—skin rash, itching, hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
• Change in vision
• New or worsening eye pain

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Eye or eyelid redness, swelling, or itching
• Pain, redness, or irritation at injection site
• Runny nose
• Sore throat

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F) or at room temperature. Do not store above 25 degrees C (77 degrees F) or expose to heat.

Refrigeration (preferred): Store it in the refrigerator. Keep it in the original carton until you are ready to take it. Remove the carton about 30 minutes before it is time for you to take the medication. Do not put the carton back into the refrigerator after it has reached room temperature. Throw away any unused medicine after the expiration date.

Room Temperature: This medicine may be stored at room temperature for up to 14 days. Keep it in the original carton until you are ready to take it. If stored at room temperature, throw away any unused medication after 14 days or after the expiration date, whichever is first.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.