What is this medicine?
DROPERIDOL (droe PER i dole) is used to prevent nausea and vomiting associated with surgery or other procedures.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Inapsine
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
- heart disease, including heart failure
- if you frequently drink alcohol-containing beverages
- irregular heart beats or slow heart rate
- kidney disease
- liver disease
- an unusual or allergic reaction to droperidol, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?
This medicine is for injection into a muscle or for slow injection into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. While this medicine may be prescribed for children as young as 2 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
- arsenic trioxide
- certain antibiotics like ciprofloxacin, clarithromycin, erythromycin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, pentamidine, sparfloxacin, telithromycin, troleandomycin
- certain medicines for cancer like daunorubicin, doxorubicin
- certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
- certain medicines for irregular heart beat like dronedarone
- general and local anesthetics
- other medicines for nausea and vomiting like dolasetron and palonosetron
- phenothiazines like chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, and trifluoperazine
- sodium phosphate salts
- tricyclic antidepressants like amitriptyline, desipramine, nortriptyline, and others
This medicine may also interact with the following medications:
- certain medicines for depression
- narcotic medicines for pain
- other medicines that prolong the QT interval (cause an abnormal heart rhythm)
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Your condition will be closely monitored following administration of this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- fainting spells or dizziness
- fast or irregular heartbeat (palpitations)
- movement difficulties
- muscle spasms or stiffness
- restlessness or agitation, nervousness
- rolling or rotating movement of the eyes
- slow or difficult breathing
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- facial flushing
- involuntary muscle movements
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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