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Measles; Mumps; Rubella; Varicella (MMRV) Vaccine Injection, Live

The MMRV vaccine stands for measles, mumps, rubella and varicella (chickenpox). It’s a live vaccine that protects you from an infection with those four viruses. It’s approved for children between ages 1 and 12.

What is this medication?

MEASLES; MUMPS; RUBELLA; VARICELLA VACCINE (MEE zuhlz; muhmps; roo BEL uh; var uh SEL uh vak SEEN) reduces the risk of measles, mumps, rubella, and varicella (chickenpox). It does not treat these infections. It is still possible to get these infections after receiving this vaccine, but the symptoms may be less severe or not last as long.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): ProQuad

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Bleeding disorder
  • Family history of immune system problems
  • Fever or infection
  • Have had a recent blood transfusion or received other blood products
  • History of fainting
  • Seizures
  • Tuberculosis
  • Weakened immune system
  • An unusual or allergic reaction to measles; mumps; rubella; varicella vaccine, other vaccines, medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

How should I use this medication?

This vaccine is injected under the skin or into a muscle. It is given by your care team.

A copy of Vaccine Information Statements will be given before each vaccination. Be sure to read this information carefully each time. This sheet may change often.

Talk to your care team to see which vaccines are right for you. Some vaccines should not be used in all age groups.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

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What may interact with this medication?

Do not take this medication with any of the following:

  • Medications that lower your chance of fighting an infection

This medication may also interact with the following:

  • Aspirin and aspirin-like medications
  • Blood products
  • Immune globulins
  • Other live virus vaccines
  • Tuberculin purified protein derivative (PPD)

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular health checks.

This is a live virus vaccine. It uses a weakened form of the virus that causes a disease. It is not likely to make you sick. It is possible to transfer the varicella virus to close contacts for up to 6 weeks after your dose. Wash your hands after using the bathroom and before preparing or handling food.

Before you receive this vaccine, talk to your care team if you have an acute illness. Vaccines can be given to people with mild acute illness, such as the common cold or diarrhea. Discuss with your care team the risks and benefits of receiving this vaccine during a moderate to severe illness. Your care team may choose to wait to give you the vaccine when you feel better.

Do not take aspirin or aspirin-like medications for 6 weeks after receiving this vaccine.

Report any side effects to your care team or to the Vaccine Adverse Event Reporting System (VAERS) website at https://vaers.hhs.gov. This is only for reporting side effects; VAERS staff do not give medical advice.

Talk to your care team if you may be pregnant. Avoid pregnancy for 3 months after receiving this vaccine.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Feeling faint or lightheaded
  • Seizures
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Fever
  • General discomfort and fatigue
  • Headache
  • Irritability
  • Muscle pain
  • Pain, redness, or irritation at injection site
  • Skin rash

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This vaccine is only given by your care team. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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