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Idarubicin injection

What is this medication?

IDARUBICIN (eye da RUE bi sin) is a chemotherapy drug. This medicine is used to treat acute myeloid leukemia (AML).

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Idamycin PFS

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • blood disorders
  • heart disease
  • infection (especially a virus infection such as chickenpox, cold sores, or herpes)
  • irregular heartbeat
  • kidney disease
  • liver disease
  • recent or ongoing radiation therapy
  • an unusual or allergic reaction to idarubicin, other chemotherapy agents, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This drug is given as an infusion into a vein. It is administered in a hospital or clinic by a specially trained health care professional. If you have pain, swelling, burning or any unusual feeling around the site of your injection, tell your health care professional right away.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

What may interact with this medication?

  • cyclophosphamide
  • medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim
  • vaccines

Talk to your doctor or health care professional before taking any of these medicines:

  • acetaminophen
  • aspirin
  • ibuprofen
  • ketoprofen
  • naproxen

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.

You may need blood work while you are taking this medication.

There is a maximum amount of this medication you should receive throughout your life. The amount depends on the medical condition being treated and your overall health. Your care team will watch how much of this medication you receive. Tell your care team if you have taken this medication before.

Do not become pregnant while taking this medication or for 6.5 months after stopping it. Women should inform their care team if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medication and for 3.5 months after stopping it. There is potential for serious harm to an unborn child. Talk to your care team for more information. Do not breast-feed an infant while taking this medication or for 14 days after stopping it.

This medication may make it more difficult to get pregnant or father a child. Talk to your care team if you are concerned about your fertility.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.
  • signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
  • signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine
  • signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness
  • agitation
  • breathing problems
  • chest pain
  • confusion
  • fast, irregular heartbeat
  • mouth sores
  • pain, swelling, redness at site where injected
  • stomach pain
  • swelling of ankles, feet, or hands

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • hair loss
  • headache
  • nausea, vomiting
  • red colored urine
  • stomach upset

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This drug is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

Terms of use.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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