Acetazolamide Injection

What is this medication?

ACETAZOLAMIDE (a set a ZOLE a mide) is a diuretic. It helps you make more urine and to lose salt and excess water from your body. It treats swelling from heart disease. It also helps treat some seizures and glaucoma.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Diamox

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• glaucoma
• kidney disease
• liver disease
• low adrenal gland function
• lung or breathing disease (COPD, chronic bronchitis, emphysema)
• an unusual or allergic reaction to acetazolamide, sulfa drugs, other drugs, foods, dyes or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medication?

This drug is injected into a vein. It is given by a health care provider in a hospital or clinic setting.

Talk to your health care provider about the use of this drug in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This drug is not for regular use.

What may interact with this medication?

Do not take this medicine with any of the following medications:

• methazolamide

This medicine may also interact with the following medications:

• aspirin and aspirin-like medicines
• cyclosporine
• lithium
• medicine for diabetes
• methenamine
• other diuretics
• phenytoin
• primidone
• quinidine
• sodium bicarbonate
• stimulant medicines like dextroamphetamine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this drug.

This drug may cause serious skin reactions. They can happen weeks to months after starting the drug. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand up or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care provider as soon as possible:

• allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
• high acid levels (trouble breathing; fast, irregular heartbeat; headache; confusion; unusually weak or tired; nausea, vomiting)
• infection (fever, chills, cough, sore throat, pain or trouble passing urine)
• liver injury (dark yellow or brown urine; general ill feeling or flu-like symptoms; loss of appetite, right upper belly pain; unusually weak or tired, yellowing of the eyes or skin)
• low red blood cell counts (trouble breathing; feeling faint; lightheaded, falls; unusually weak or tired)
• redness, blistering, peeling, or loosening of the skin, including inside the mouth
• unusual bruising or bleeding

Side effects that usually do not require medical attention (report to your doctor or health care provider if they continue or are bothersome):

• decreased hearing, ringing of the ears
• diarrhea
• increased thirst
• kidney stones (blood in the urine; pain when urinating; pain the lower back or side)
• loss of appetite
• nausea
• pain, tingling, numbness in the hands or feet
• unusual sweating
• vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This drug is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.