Japanese Encephalitis Virus Vaccine (JE-VAX)

The JEV vaccine prevents Japanese encephalitis virus infections. This infection results from a mosquito bite. Your provider may recommend this vaccine if you’re traveling to Asia or the western Pacific, and plan to stay for more than four weeks.

What is this medication?

JAPANESE ENCEPHALITIS VIRUS VACCINE (jap uh NEEZ en sef uh LAHY tis VAHY ruhs vak SEEN) is a vaccine. It is used to help prevent Japanese encephalitis infections. You cannot get the disease from the vaccine.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): JE-VAX

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • allergic reaction like hives after insect bites or unknown cause
  • asthma
  • drink alcohol-containing drinks
  • immune system problems
  • an unusual or allergic reaction to Japanese encephalitis virus vaccine, other medicines, thimerosal, gelatin, polysorbate 80, mouse protein, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This vaccine is for injection under the skin. It is given by a health care professional. Usually, three doses are given. You will be observed for at least 30 minutes after a dose.

A copy of Vaccine Information Statements will be given before each vaccination. Read this sheet carefully each time. The sheet may change frequently.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 1 year of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

Keep appointments for follow-up (booster) doses as directed. It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

What may interact with this medication?

  • medicines that suppress your immune system like medicines for cancer
  • steroid medicines like prednisone or cortisone
  • vaccines

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

This vaccine may not fully protect everyone. This vaccine does not prevent all types of encephalitis. Protect yourself from mosquito bites.

Stay in an area where you have ready access to medical care for at least 10 days after a vaccine dose. Get immediate medical care at the beginning of any reaction.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • changes in vision
  • confusion
  • feeling faint or lightheaded, falls
  • pain, tingling, numbness in the hands or feet
  • seizures
  • trouble passing urine or change in the amount of urine

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • dizziness
  • fever
  • headache
  • irritation or pain at site where injected
  • muscle pain or weakness
  • nausea, vomiting
  • unusually weak or tired

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This vaccine is only given in a clinic, pharmacy, doctor's office, or other health care setting and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

Terms of use.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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