What is this medication?
CISAPRIDE (SIS a pride) is used to treat heartburn in patients with gastroesophageal reflux disease (GERD). Because of the serious risks associated with this medicine it should only be used when lifestyle changes and other medicines have not worked. This medicine in only available from your doctor, who must register with the drug company and meet certain criteria for the use of this drug. Cisapride has not been available in pharmacies since August 2000. For information, the manufacturer has provided the following toll-free number (877) 795-4247.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Propulsid
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
•eating disorder, like anorexia or bulimia
•heart disease or heart failure
•heart rhythm problems
•heart valve problems
•history of low levels of calcium, potassium, or magnesium
•stomach bleeding, blockage, or ulceration
•an unusual or allergic reaction to cisapride, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
How should I use this medication?
Take this medicine by mouth with a glass of water. Follow the directions on the label. Take this medicine on an empty stomach, at least 15 minutes before eating and at bedtime. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medication?
Do not take this medicine with any of the following medications:
- antiviral medicines for HIV or AIDS
- arsenic trioxide
- certain antibiotics like ciprofloxacin, clarithromycin, dalfopristin, quinupristin, erythromycin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, pentamidine, sparfloxacin, telithromycin, troleandomycin
- certain medicines for cancer like daunorubicin, doxorubicin, imatinib
- certain medicines for depression, anxiety, or other psychotic disturbances like clozapine, haloperidol, pimozide, risperidone
- certain medicines for erectile dysfunction like sildenafil, tadalafil, vardenafil
- certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
- certain medicines for irregular heart beat like amiodarone, disopyramide, bretylium, dofetilide, dronedarone, flecainide, ibutilide, procainamide, propafenone, quinidine, sotalol
- general and local anesthetics
- grapefruit juice
- other medicines that prolong the QT interval (cause an abnormal heart rhythm)
- phenothiazines like chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, promethazine, thioridazine, trifluoperazine
- sodium phosphates
This medicine may also interact with the following medications:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your doctor or health care professional for regular checks on your progress. For this medicine to work properly it is important to make lifestyle changes. Eat smaller meals, elevate the head of your bed 6 to 8 inches, avoid high-fat foods, chocolate, alcohol, smoking, caffeine and carbonated drinks.
If you have any fainting spells or rapid or irregular heartbeat, stop taking this drug immediately. Contact your health care professional right away for evaluation.
Do not drink grapefruit juice while you are taking this medicine. Grapefruit juice could increase your risk of having serious side effects from this medicine.
What side effects may I notice from receiving this medication?
Side effects that you should report to your doctor or health care professional as soon as possible:
•fainting or falling spells
•rapid or irregular heartbeat
•unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
•diarrhea or constipation
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medication?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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