Clostridium perfringens is a common food poisoning caused by C. perfringens bacteria. It causes diarrhea and stomach cramps. You usually get it from eating contaminated meat or poultry that’s been left out for too long. C. perfringens food poisoning usually isn’t serious and goes away on its own.
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Clostridium perfringens food poisoning is an illness you can get from eating food contaminated with C. perfringens bacteria. It’s common and usually not serious. It causes abdominal (belly) cramps and watery diarrhea. Symptoms last for a day or two.
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C. perfringens bacteria also causes more serious conditions when it infects wounds, including gas gangrene and anaerobic cellulitis.
Abdominal cramps and watery diarrhea are the most common symptoms of C. perfringens food poisoning. It usually doesn’t cause vomiting or fever. Symptoms start six to 24 hours after you eat contaminated food.
Food contaminated with C. perfringens bacteria causes this kind of food poisoning. The bacteria is found in nature. It can create spores, which are like a protective suit that allows bacteria to survive extreme conditions, like heat or cold. These spores can’t reproduce, but they can contaminate food, even after it’s cooked.
The bacteria can reproduce again when the food gets cool (between 40 and 140 degrees Fahrenheit, or 4 and 60 degrees Celsius) for an hour or longer without being rewarmed or refrigerated.
When you eat food contaminated with the bacteria, they release toxins into your intestines. The toxins cause inflammation, leading to diarrhea and cramping.
You can get C. perfringens from eating food that’s been sitting out, even if it’s just for an hour or two. C. perfringens is most commonly found in:
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It’s less common in fish and vegetables.
C. perfringens food poisoning rarely leads to complications. But you can get dehydrated if you have severe diarrhea.
If bacteria get into your bloodstream, they can cause sepsis, a life-threatening reaction to infection. This is a very rare complication of food poisoning.
Providers usually diagnose food poisoning based on your symptoms rather than testing.
If they need to test you, you’ll provide a stool (poop) sample. Your provider will send the sample to a lab, where they’ll test it for C. perfringens and other germs that can make you sick.
If there’s an outbreak of sickness, health officials may test food to find the source of the bacteria.
There’s no specific treatment for food poisoning caused by C. perfringens. It usually goes away on its own within a day or two. If you’re very sick, your provider will treat you with antibiotics. But this usually isn’t necessary.
Anytime you have diarrhea or are throwing up, it’s important to take care of yourself by:
C. perfringens food poisoning usually isn’t serious. Even without treatment, you should feel better within a couple of days.
See a provider if your symptoms don’t get better within a few days or if you have severe diarrhea or vomiting.
Go to the nearest emergency room if you experience symptoms of serious illness, including:
You can avoid food poisoning by taking precautions when heating, storing and serving food. These include:
Clostridium perfringens (C. perfringens) food poisoning is common. It can be unpleasant, but it’s usually not serious. Drink plenty of fluids and don’t hesitate to contact a healthcare provider if you’re not getting better within a few days.
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Cleveland Clinic’s health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards.
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