Juvenile nasopharyngeal angiofibroma (JNA) is a fast-growing, noncancerous growth that forms behind your nose. Surgical removal is the standard treatment. But even after removal, the tumor can come back. JNA has a high survival rate, but it may require lifelong management.
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Juvenile nasopharyngeal angiofibroma (JNA) is a rare, noncancerous tumor that grows behind your nose. It’s a vascular growth, which means it’s mostly filled with blood vessels.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
Breaking down the condition’s name is the best way to understand it:
JNA isn’t cancerous. But it’s still serious and aggressive. Nasopharyngeal angiofibroma can spread from your nasal cavity into your sinuses, skull and brain. Without treatment, JNA may lead to life-threatening complications or death. That’s why it’s so important to tell a healthcare provider if something doesn’t seem right. The good news is that treatment can help get rid of the tumor.
Juvenile angiofibroma is most common in males between the ages of 10 and 25. Very rarely, it may occur in males over 25 or as young as 7. JNA almost never affects females.
Nasopharyngeal angiofibroma is very rare. Experts estimate it occurs in 1 in every 150,000 to 1,500,000 people.
JNA symptoms aren’t immediate. They often start once the tumor grows large enough to interfere with nasal airflow. Juvenile nasopharyngeal angiofibroma symptoms may include:
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Researchers don’t fully understand what causes juvenile nasopharyngeal angiofibroma. Because these tumors occur almost exclusively in males, hormones likely play a role. Experts don’t believe JNA tumors run in families.
There aren’t a lot of clear-cut risk factors for JNA. Even though the condition isn’t hereditary, you’re more likely to develop JNA if one of your biological family members has another condition called familial adenomatous polyposis (FAP). Experts continue to explore the relationship between these two conditions.
If JNA grows, it can press on surrounding facial structures and cause complications like:
A healthcare provider can diagnose JNA during an examination. They’ll look at your nose and ask about your symptoms. They’ll likely need to run tests, which may include:
They may also refer you to an otolaryngologist (ENT) to run more tests or confirm the diagnosis.
Healthcare providers use surgery and radiation therapy to treat JNA.
Surgical removal of the tumor is the go-to JNA treatment. A surgeon uses an endoscope (a thin tube with a camera) to do the procedure through your nostrils. That way, they can avoid making cuts (incisions) on the outside of your nose.
In some cases, surgeons might need to make external incisions. If that happens, they’ll make them as small as possible to minimize scarring.
As your nose contains so many blood vessels, providers usually do a procedure called embolization beforehand. Embolization helps prevent blood loss during surgery.
It can be hard for surgeons to remove tissue that’s grown into surrounding bone and/or sinuses. If tiny bits of tissue are left behind, the tumor may come back. If that happens, your surgeon might recommend repeat surgery or radiation therapy.
According to some research studies, JNA comes back in up to 37% of cases.
Keep an eye on sudden symptoms like nasal stuffiness or frequent nosebleeds. You know your body better than anyone else. Be sure to tell a healthcare provider when something doesn’t seem right to you.
JNA has a high survival rate. The outlook is good with treatment.
Because JNA can come back, there’s a chance you might need radiation therapy or an additional surgery in the future. Your healthcare provider can check in with you periodically and recommend treatment if necessary.
Juvenile nasopharyngeal angiofibroma (JNA) isn’t cancer. But it still requires prompt treatment. Because the tumor can grow into nearby areas quickly, it’s important to remove it as soon as possible. Talk to your healthcare provider about what to expect.
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If you have conditions affecting your ears, nose and throat, you want experts you can trust. Cleveland Clinic’s otolaryngology specialists can help.
Last reviewed on 04/30/2025.
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