IRB Study Number 23-1099
Status Recruiting
Locations Cleveland Clinic Weston Hospital , Cleveland Clinic Main Campus
Institutes Digestive Disease & Surgery Institute, Neurological Institute, Taussig Cancer Institute
Description
This registry is for Latino/Hispanic adults who receive care at Cleveland Clinic and either:
have colorectal cancer (CRC),
have Parkinson’s disease (PD), or
are healthy Latino controls without these conditions.
The goal is to build a long-term Latino health cohort so researchers can better understand how genetics, lifestyle, environment, and access to care affect the risk of colorectal cancer and Parkinson’s disease, and health in general for Latino communities.
If you join, you will be asked to:
Complete a questionnaire about your health, background, lifestyle, and family history,
Provide a blood sample or saliva sample (one-time), and
Allow the study team to use information from your medical record and stored tissue samples (if available) for research.
Your samples and data may be stored for future approved studies. You may also be contacted in the future to complete short follow-up questionnaires or give another sample, if you agree. There are no experimental treatments, and this registry does not change your usual medical care.
Inclusion Criteria
General (all participants)
Age 18 years or older
Self-identify as Hispanic or Latino
Colorectal cancer (CRC) cohort
- Diagnosis of a primary cancer of the colon, rectosigmoid junction, or rectum
Parkinson’s disease (PD) cohort
- Diagnosis of Parkinson’s disease based on standard neurologic criteria
Control cohort (healthy controls)
No history of colorectal cancer or Parkinson’s disease
Meet the general criteria above
Exclusion Criteria
CRC cohort:
- No specific medical exclusion criteria
PD cohort:
- No specific medical exclusion criteria
Control cohort (healthy controls):
Any evidence of past or present colorectal cancer
Any evidence of past or present Parkinson’s disease
Any related neurological disorder similar to Parkinson’s disease
