Details

IRB Study Number 21-179

Status Recruiting

Phase Not Applicable

Location U Building - Mellen Center

Institute Neurological Institute

Description

Description

The purpose of this study is to determine MRI biomarkers, describe unique MRI features, and determine clinical and MRI predictors of clinical outcomes of myelin oligodendrocyte glycoprotein antibody (MOG-IgG1) associated disorders (MOGAD). This will help characterize the MRI features of MOGAD, and differentiate these from aquaporin-4 (AQP4-IgG) neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS).

Participants will be asked to complete one visit. Activities include a 7T MRI scan with or without contrast and optional blood sample collection.

Inclusion Criteria

Inclusion Criteria

  • Age 18-99 years
  • Diagnosis of MOGAD, multiple sclerosis (MS) or are a healthy control

Exclusion Criteria

Exclusion Criteria

  • Contraindication to MRI scans