IRB Study Number 19-411
Status Recruiting
Phase Not Applicable
Location Cleveland Clinic Main Campus
Institute Neurological Institute
Description
Deep brain stimulation (DBS) is an effective treatment for Parkinson's disease (PD), but we have limited knowledge as to how it works. This study involves the use of a specific type of MRI called functional magnetic resonance imaging (fMRI). The fMRI takes pictures of the brain while you do specific tasks. By analyzing these pictures, we can determine the specific areas of the brain that are active during DBS and contribute to the improvement of motor symptoms.
Inclusion Criteria
- Confirmed diagnosis of Parkinson's disease
- Undergone deep brain stimulation surgery targeting the subthalamic nucleus
- Willingness to lie still for an extended period inside the MRI scanner
- Willingness to stop taking medications for 12 hours prior to the scans
Exclusion Criteria
- Presence of other neurological deficits or disorders
- Previous history of major surgeries other than DBS for movement disorders
- Severe psychiatric or behavioral problems
- Evidence of dementia
- Claustrophobia
- Any contraindications to MRI (pacemakers, shunts, aneurysm clips, or stents)
