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Treatments & Procedures

Steroid Injections

What are steroids?

Steroids (short for corticosteroids) are man-made drugs that closely resemble cortisol, a hormone that your adrenal glands produce naturally. Corticosteroids are different from the male hormone-related steroid compounds that some athletes abuse.

Steroids work by decreasing inflammation and reducing the activity of the immune system. Steroids are used to treat a variety of inflammatory diseases and conditions.

How are steroids given?

Steroid medications are available in several forms that vary in how easily they dissolve or how long they stay in the body.

Steroids may be given systemically, which means throughout the "system" or body, or locally to the precise place where a problem exists.

Systemic steroids can be given either through a vein (intravenously), into a muscle (intramuscularly), or by mouth (orally). Local steroids can be given as eye drops, ear drops, or skin creams and by direct injection into joints, bursae (lubricating sacs between certain tendons and the bones beneath them), or around tendons or other soft tissue areas.

Why are steroids injected?

Injecting steroids into one or two local areas of inflammation allows doctors to deliver a high dose of medication directly to the problem area. When doctors give steroids by mouth or intravenously, they cannot be sure an adequate amount of the steroid will eventually reach the problem area.

What conditions are treated with steroid injections?

Steroids are often injected directly into joints to treat conditions such as rheumatoid arthritis, gout or other inflammatory diseases. Steroids can also be injected into inflamed bursae, or around tendons near the shoulder, elbow, hip, knee, hand or wrist.

When will my doctor prescribe steroid injections?

The decision to prescribe steroids is always made on an individual basis. Your doctor will consider your age, physical activity and other medications you are taking. Your doctor will also make sure you understand the potential benefits and risks of steroid injections.

When should steroid injections not be used?

Steroids should not be injected when there is infection in the area to be injected or elsewhere in the body. If a joint is already severely destroyed, injections are not likely to benefit.

If a patient has a potential bleeding problem or is taking anticoagulants (often referred to as blood "thinners"), steroid injections may cause bleeding at the site. For these patients, injections are only given with great caution.

Frequent steroid injections, more often than once every 3 or 4 months, are not recommended because of the increased risk of weakening tissues in the treated area.

What are the expected benefits of steroid injections?

Local injections are generally well-tolerated and are less likely to produce serious side effects than other forms of steroid medications.

Before a joint is injected with a steroid, joint fluid may be removed for testing. Testing the joint fluid is especially important if the diagnosis is uncertain. Steroid injections often reduce joint inflammation, helping preserve joint structure and function.

Steroid injections may help avoid the need for oral steroids or increased doses of oral steroids, which could have greater side effects.

What are the potential disadvantages of steroid injections?

Steroid injections are one of the most effective ways to decrease pain and improve function, yet they generally do not cure the illness.

In rare instances, the following side effects might occur:

  • Infection
  • Allergic reactions
  • Local bleeding
  • Rupture of a tendon
  • Skin discoloration

Excessively frequent, repeated injections into the same area can cause the bone, ligaments, and tendons to weaken.

Does everyone have side effects?

Not everyone will develop side effects. How often any side effect occurs varies from patient to patient. If steroid injections are infrequent (less than every 3 to 4 months), it is possible that none of the listed side effects will occur.

What role do steroid injections play in an overall treatment program?

Steroid injections can be added to a treatment program that may already include analgesics, anti-inflammatory medications, physical therapy, occupational therapy, and/or supportive devices such as canes and braces. Whether one or more of these treatment methods are used depends on the nature of the problem. For example, in an otherwise healthy individual, tendinitis may be adequately treated with only a local steroid injection. However, in a patient with rheumatoid arthritis, injections are generally a small part of a multi-faceted treatment approach.

References

National Jewish Health.
About Steroids.
www.nationaljewish.org/healthinfo/medications/lung-diseases/longterm/about-steroids.aspx.
Accessed 8/30/2010

Nieman LK, Pharmacologic use of glucocorticoids.
www.uptodate.com/online/content/topic.do?topicKey=adrenal/12178&selectedTitle=2%7E150&source=search_result.
Accessed 8/30/2010

Jacobs, JWJG, Bijlsma JWJ. Glucocorticoid Therapy.
In: Firestein: Kelley’s Textbook of Rheumatology, 8th ed. Philadelphia, PA: WB Saunders Co.; 2008.
www.mdconsult.com/das/book/body/223348568-2/0/1807/387.html?tocnode=55732258&fromURL=387.html.
Accessed 8/30/2010

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This information is provided by the Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition. This document was last reviewed on: 10/18/2010...#4934