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Fexofenadine Capsules or Tablets

Fexofenadine is an antihistamine medication that comes in a capsule or tablet form. It treats and prevents symptoms of allergies like itchy eyes, sneezing and hives. It works by blocking histamine in your body. A common brand name of this medication is Allegra®.

What is this medication?

FEXOFENADINE (fex oh FEN a deen) prevents and treats allergy symptoms, such as red, itchy eyes, sneezing, a runny or stuffy nose, or hives. It works by blocking histamine, a substance released by the body during an allergic reaction. It belongs to a group of medications called antihistamines.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Allegra, Allegra Allergy 12 Hour, Allegra Allergy 24 Hour, Allegra Children's Allergy, Allergy Relief

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Kidney disease
  • An unusual or allergic reaction to fexofenadine, terfenadine, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

Take this medication by mouth with a full glass of water. Follow the directions on the prescription label. You may take this medication with food or on an empty stomach. Take your medication at regular intervals. Do not take it more often than directed. You may need to take this medication for several days before your symptoms improve.

Talk to your care team regarding the use of this medication in children. While this medication may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

  • Antacids
  • Erythromycin
  • Grapefruit, apple, or orange juice
  • Ketoconazole
  • Magnesium-containing products

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Visit your care team for regular checks on your health. Tell your care team if your symptoms do not start to get better or if they get worse.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions or angioedema—skin rash, itching, hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Cough
  • Drowsiness
  • Dry mouth
  • Headache
  • Upset stomach

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77degrees F). Protect from moisture. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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