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Ribavirin tablets

Ribavirin is an antiviral medication that works with other medications to treat hepatitis C. This condition is a virus that causes chronic liver inflammation. This medication comes in a tablet form that you can take by mouth with a glass of water.

What is this medication?

RIBAVIRIN (rye ba VYE rin) is an antiviral medicine. It is used with other medicines to treat hepatitis C. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Copegus, Moderiba, RibaPak, Ribasphere, Ribasphere RibaPak, RibaTab

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • cancer
  • blood disease like sickle-cell or thalassemia
  • diabetes
  • drug abuse or addiction
  • heart disease
  • history of depression, anxiety
  • immune system problems
  • kidney disease
  • low blood counts, like low white cell, platelet, or red cell counts
  • lung or breathing disease, like asthma
  • man with a partner who is pregnant or trying to get pregnant
  • other liver disease
  • thyroid disease
  • an unusual or allergic reaction to ribavirin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 5 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

If you miss a dose and remember the same day, take it as soon as you remember. If the whole day has passed, ask your healthcare provider what to do. Do not take double or extra doses.

What may interact with this medication?

Do not take this medicine with the following medication:

  • didanosine

This medicine may also interact with the following medications:

  • abacavir
  • azathioprine
  • emtricitabine
  • lamivudine
  • stavudine
  • zidovudine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

See your care team for a follow-up visit as directed. You may need to have tests done to check your progress. Tell your care team if your symptoms do not improve or if they get worse.

This medication may cause birth defects or death to an unborn child. Women taking this medication must avoid pregnancy while taking this medication and for 9 months after stopping this medication. Men who are taking this medication must avoid getting a woman pregnant while taking this medication and for 6 months after stopping this medication. Use 2 forms of birth control. Women who can still have children must have a negative pregnancy test before starting treatment. Take monthly pregnancy tests while you are taking this medication and for 9 months after this medication is stopped. Talk to your care team if you think that you or your partner are pregnant or are trying to become pregnant.

Do not drink alcohol, including beer, wine, and liquor. This may make your liver disease worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe. Brush your teeth thoroughly twice daily and have regular dental examinations. Also, if you vomit, rinse out your mouth.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • back or stomach pain
  • black or bloody diarrhea
  • breathing problems
  • changes in vision
  • chest pain
  • dark urine
  • depressed mood, thoughts of suicide
  • dizziness, lightheaded
  • fever or chills, sore throat
  • general ill feeling or flu-like symptoms
  • light-colored stools
  • loss of appetite, nausea
  • missed menstrual period
  • right upper belly pain
  • unusual bleeding or bruising
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • cough
  • difficulty hearing or ringing in the ears
  • increased hunger or thirst
  • increased urination
  • itchy skin

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

Terms of use.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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