Emergency icon Important Updates
Department Rheumatologic and Immunologic Disease
Primary Location Lorain Family Health Center
Type of Doctor Adults Only
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Administration of Injectable Medications for Osteoporosis
  • Adult Rheumatology
  • Bone Density Testing
  • Clinical Trials
  • Cortisone Injections
  • Dual Energy X-Ray Absorptiometry (DXA)
  • General Rheumatology
  • Hyaluronic Acid (HA)
  • Hyaluronic Acid Injections
  • Immunoglobulin Infusion
  • Immunotherapy
  • Infusion Therapy
  • Infusions of Biologic Agents on Site
  • Joint Aspiration
  • Joint Preservation Center
  • Medical Management of Early Osteoarthritis
  • Medication Management
  • Musculoskeletal Evaluation
  • Musculoskeletal Medicine
  • Musculoskeletal Treatment for Joint Pain
  • Osteoporosis Diagnosis
  • Rheumatoid Arthritis: How to Treat
  • Rheumatology
  • Steroid Injections
  • Therapeutic Injections
  • Viscosupplementation
View all 26 Treatment & Services +

Specialty in Diseases & Conditions

  • AIDS
  • Ankylosing Spondylitis
  • Antiphospholipid Syndrome
  • Arthritis
  • Arthritis of the Elbow
  • Arthritis of the Hand
  • Arthritis of the Hip
  • Arthritis of the Knee
  • Arthritis of the Shoulder
  • Arthritis of the Thumb Base
  • Arthritis of the Wrist
  • Autoimmune Disease
  • Autoinflammatory Syndromes
  • Behcet's Disease
  • Benign Hypermobility Joint Syndrome
  • Buerger's Disease
  • Bursitis
  • Calcification Tendinitis
  • Calcinosis
  • Central Nervous System Vasculitis
  • Chondrocalcinosis (Pseudo Gout)
  • Churg-Strauss Syndrome
  • Connective Tissue Diseases
  • Connective Tissue Disorders
  • Cryoglobulinemia
  • Dermatomyositis
  • Eosinophilic Granulomatosis with Polyangiitis (EGPA)
  • Familial Mediterranean Fever (FMF)
  • Giant Cell Arteritis
  • Gout
  • Gout Arthritis
  • Granulomatosis with Polyangiitis (Wegener’s)
  • Hand Pain
  • Hand Problems
  • Henoch-Schonlein Purpura
  • Hip Disorders
  • Hip Pain
  • HIV
  • Immunodeficiency
  • Immunosuppression
  • Iritis
  • Joint Disorders
  • Joint Pain
  • Knee Joint Disorders
  • Knee Pain
  • Lupus
  • Lupus Anticoagulant
  • Lupus Nephritis
  • Metabolic Bone Disease
  • Metabolic Diseases
  • Microscopic Polyangiitis (MPA)
  • Musculoskeletal Disorders
  • Musculoskeletal Impairments
  • Musculoskeletal Pain
  • Myositis
  • Osteoarthritis
  • Osteoarthritis of the Hips in the Elderly
  • Osteoarthritis of the Knees in the Elderly
  • Osteopenia
  • Osteoporosis
  • Osteoporosis in Men
  • Osteoporosis Related to Cancer
  • Paget's Disease
  • Painful Joints
  • Palindromic Rheumatism
  • Panuveitis
  • Polyarteritis Nodosa
  • Polymyalgia Rheumatica
  • Polymyositis
  • Pseudogout
  • Psoriatic Arthritis
  • Radiculopathy
  • Raynaud's Phenomenon
  • Reactive Arthritis
  • Relapsing Polychondritis
  • Retroperitoneal Fibrosis
  • Rheumatoid Arthritis
  • Rheumatoid Arthritis and Heart Disease
  • Rheumatoid Vasculitis
  • Sacroiliitis
  • Sarcoidosis
  • Scleritis
  • Scleroderma
  • Shoulder Pain
  • Sjogren's Syndrome
  • Spondylitis
  • Spondyloarthropathy
  • Spondylosis
  • Steroid-Induced Osteoporosis
  • Systemic Autoimmune Diseases
  • Systemic Lupus Erythematosus
  • Takayasu's Arteritis
  • Temporal Arteritis
  • Tendinosis
  • Tendonitis
  • Tenosynovitis
  • Trigger Finger
  • Uveitis
  • Vitamin D Deficiency
View all 99 Specialties +


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About Margaret Tsai, MD

Margaret Tsai, MD, is an Associate Staff Member in the Department for Rheumatic and Immunologic Disease. She earned her medical degree from Northeast Ohio Medical University in Rootstown, Ohio. She completed an Internal Medicine residency at Summa Health System in Akron, Ohio and an Adult Rheumatology fellowship at University Hospitals of Cleveland/Case Western Reserve University in Cleveland, Ohio.

She is a member of several professional societies, including the American College of Rheumatology and the American College of Physicians.

Dr. Tsai has presented and participated in research on a variety of adult rheumatology subjects, including osteoarthritis, rheumatoid arthritis, lupus, and other autoimmune diseases.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - University Hospitals of Cleveland
Cleveland, OH

Residency - Summa Health System
Internal Medicine
Akron, OH

Internship - Summa Health System
Internal Medicine
Akron, OH

Medical Education - Northeast Ohio Medical University
Rootstown, OH

Undergraduate - Kent State University
Kent, OH


  • Internal Medicine - Rheumatology

Specialty Interests

Adult rheumatology and osteoporosis

Research & Publications

Research & Publications

See publications for Margaret Tsai, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/3/2024, Dr. Tsai has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Tsai receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • CarelonRx

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

454 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 5
Patient Rating of Doctor 4.9

118 Patient Comments

Reviewed on Jun 14, 2024

Dr. Tsi is the ABSOLUTE BEST!!!

Reviewed on Jun 11, 2024

I actually had to wait for 5 months to get an appointment. She's a very busy Dr.

Reviewed on Jun 4, 2024

Dr Tsai is one of the nicest doctors I've seen over my lifetime

Reviewed on Jun 3, 2024

Dr. Tsai has the Best Team

Reviewed on May 30, 2024

She is so nice and caring, couldn't ask for a better doctor.

Reviewed on May 24, 2024

Always a joy to meet with Dr. Tsai and her staff.

Reviewed on May 24, 2024

Doctor is always very understanding and explains everything to you

Reviewed on May 20, 2024

Very friendly Dr and staff

Reviewed on May 17, 2024

Dr. Tsai is a wonderful doctor to be working with!

Reviewed on May 17, 2024

Dr. Tsai and her team are amazing in every way with their commitment and care of their patients.

Reviewed on May 17, 2024

Dr TSAI listened to my issues and took my concerns and issues and made it so much easier to deal with the diagnosis.

Reviewed on May 14, 2024

Dr Psai is very caring and excellent in every way

Reviewed on May 14, 2024

Love Dr. Tsai! Always very professional & responsive to care needed.

Reviewed on May 14, 2024

Dr. Tsai gets a 10 from me! This says it all!

Reviewed on May 14, 2024

Dr Tsai is an exemplary Rheumatologist. She is Personable and kind, always addresses all my concerns patiently and with empathy.

Reviewed on May 13, 2024

I had to wait for 6 months to get an appointment, but it was worth the wait. Dr Tsai is an awesome Doctor!!

Reviewed on May 13, 2024

Dr Thai exceeded the highest available rating. I was impressed with her compassion , knowledge and communication skills.

Reviewed on Apr 30, 2024

Dr. Tsai is one of the best doctors I have ever had. She is amazingly understanding and kind. She makes you feel comfortable and actually listens.

Reviewed on Apr 25, 2024

Dr Tsai is amazing! Her patient skills or what we use to call bed side manners is 12 on a 10 scale.

Reviewed on Apr 23, 2024

Excellent experience. Dr. Tsai always is concerned about my well being

Reviewed on Apr 22, 2024

This doctor and staff are always respectful, prompt and efficient.

Reviewed on Apr 16, 2024

I moved over 25 miles away but continue to see her because she's so wonderful!

Reviewed on Apr 16, 2024

She is a great doctor!

Reviewed on Apr 15, 2024

Dr. Tsai is knowledgeable, concerned and kind. She has a special talent for making her patients feel comfortable and informed. I highly recommend had and appreciate the care she provides to me everytime I have a ppontment .

Reviewed on Apr 15, 2024

Dr. Tsai exemplifies everything an excellent physician should be. Stellar in every way.

Reviewed on Apr 8, 2024

Dr. Tsai is the nicest, most caring doctor we've seen. She truly cares about her patients!

Reviewed on Apr 2, 2024

Dr. Tsai is an extraordinary physician . . . . Caring, empathetic, kind, knowledgeable.

Reviewed on Apr 1, 2024

I love Dr. Tsai! She listens to you and is very caring. Such a nice person!!

Reviewed on Mar 29, 2024

Tremendous respect and care from Dr Tsai

Reviewed on Mar 28, 2024

Dr.Tsai is always very understanding and has cares about my condition for 11 years now!!

Reviewed on Mar 5, 2024

Dr Tsai is definitely one of the BEST Doctors I have ever had the pleasure of seeing! I HIGHLY recommend her to anyone! She is very caring, knowledgeable, kind, thoughtful and thorough. She is absolutely GREAT!

Reviewed on Mar 4, 2024

She is a keeper! How lucky is Cleveland clinic to have her!

Reviewed on Mar 1, 2024

She discussed all the future treatments.

Reviewed on Feb 27, 2024

Dr. Tsai is focused the well being of her patient. She is great at diagnosis and extremely thorough. She familiarizes herself with patient history before each appointment.She has helped me immensely. I'm grateful for her and feel I am in good hands.

Reviewed on Feb 27, 2024

I couldn't ask for a better doctor. She's wonderful.

Reviewed on Feb 22, 2024

Dr Tsai is the most personable and friendly physician I have ever known.

Reviewed on Feb 20, 2024

I love my Doctor she is Amazing

Reviewed on Feb 19, 2024

She's very patient and always goes step by step when reviewing my labs. Explains very thoroughly the results.

Reviewed on Feb 19, 2024

Dr. Tsai is a great asset to the Cleveland Clinic. She is a joy to visit and is very personable.

Reviewed on Feb 19, 2024

She is a wonderful doctor...One of the best

Reviewed on Feb 9, 2024

Always great care with Dr. Tsai and her team.

Reviewed on Feb 8, 2024

Dr Tsai and her staff are amazing!!!

Reviewed on Feb 6, 2024

Outstanding Dr.-her entire team!

Reviewed on Feb 6, 2024

Fabulous Dr. & the entire team I encountered that day

Reviewed on Feb 2, 2024

Dr Tsai is outstanding. She takes the time to listen to your concerns and works with you on a plan to maintain and improve your health.

Reviewed on Jan 30, 2024

Dr M Tsai & her staff go above & beyond to have you feel comfortable, & well cared for

Reviewed on Jan 30, 2024

Dr. Tsai is very caring and listens to my explanations of how I have been feeling.

Reviewed on Jan 29, 2024

Dr. Tsai is the best care provider I have had. Recommended her to anyone with similar needs as my own.

Reviewed on Jan 26, 2024

I've always had a great experience with Dr. Tsai office.

Reviewed on Jan 26, 2024

Dr.Tsai is a wonderful caring doctor. She always makes me feel better when I leave. I've recommend her to others.

Reviewed on Jan 26, 2024

Dr Tsai is excellent and very understanding.

Reviewed on Jan 25, 2024

Dr. Tsai is my favorite doctor. She's kind, empathetic, and truly listens. She cares about her patients. I am lucky to have her on my team because I know I can trust her and she'll always have my best interest in health in mind. I have seen many doctors in different specialties and have learned this is a rare quality to have. Dr. Tsai is genuinely the best.

Reviewed on Jan 18, 2024

I have recommended Dr. Tsai to several people.

Reviewed on Jan 15, 2024

Dr. Tsai and her staff are excellent.

Reviewed on Jan 11, 2024

Dr Tsai and staff do a great job !

Reviewed on Jan 5, 2024

Such an enjoyable visit. I am 60 years old and have never had a doctor this knowledgeable and thorough. She was a pleasant surprise. I wish I could have Dr. Tsai as my primary care physician.

Reviewed on Jan 5, 2024

Dr Tsai is very sweet and kind. She shows genuine concern for how her patients are doing.

Reviewed on Dec 21, 2023

Could tell she read through my chart in detail before coming in and remembers so many non-medical details too. Efficient without feeling rushed, felt reassured without ever feeling dismissed.

Reviewed on Dec 21, 2023

All good. Love Dr Tsai

Reviewed on Dec 19, 2023

I received excellent care from Dr. Tsai.

Reviewed on Dec 18, 2023

Dr. Tsai is outstanding across the board.

Reviewed on Dec 15, 2023

I love Dr. Tsai, however...She seems extremely rushed. She finishes almost every one of my sentences as soon as I start talking. This is EXTREMELY FRUSTRATING. It causes me to lose my train of thought.As I said, I really, really, like Dr. Tsai, but trying to see her in a timely manner is absolutely out of the question. And that sucks.It would be a much more satisfying visit if only I were allowed a few more, less rushed, minutes and if she would slow down at least long enough to allow me to finish my thoughts in MY words.-Peace

Reviewed on Dec 8, 2023

I highly recommend Dr. Tsai - she came very well recommended to me and lived up to their praise of her attitude, knowledge, and skills. She is at the top of my list for friends and family who may need this type of care in the future.

Reviewed on Dec 8, 2023

I did recommend but she called in Oct. And couldn't get in until April 2024. She was in pain and couldn't wait.

Reviewed on Dec 5, 2023

Already recommended Dr Margaret a friend of mine. Dr Margaret's amazing she always listens and takes time out of her busy schedule to take care of everyone

Reviewed on Dec 5, 2023

I love my visits with Dr. Tsai! She and her staff are so very caring

Reviewed on Dec 5, 2023

She is the best! She listens and really cares!

Reviewed on Nov 21, 2023

Dr Tsai is an incredible physician with exceptional people skills.

Reviewed on Nov 20, 2023

Dr. Tsai is wonderful. We need to schedule appts. Many months in advance as she is extremely busy and not always available.Sometimes I'm on hold waiting for a person to pick up the phone.

Reviewed on Nov 20, 2023

Dr. Tsai is extremely warm, caring, and compassionate.

Reviewed on Nov 3, 2023

Is there a 10! Dr Tsai is a very knowledgeable caring doctor

Reviewed on Nov 3, 2023

Love Dr. Tsai

Reviewed on Nov 3, 2023

Dr Tsai pointed out my wrist had already naturally fused, so having the surgery would take a lot of the pain away. No one else pointed that out!

Reviewed on Oct 30, 2023

Dr Tsai always listens. Make you feel comfortable.

Reviewed on Oct 27, 2023

I would highly recommend Dr. Tsai. She is the most compassionate doctor I have ever had! Dr.Tsai really listens, never made me feel rushed or as though I was just another patient! She showed genuine concern and empathy for my symptoms!

Reviewed on Oct 24, 2023

My experience with dr Tsai was the best Dr, patient experience I have ever had. She is the nicest,most caring, empathetic doctor I have ever met.

Reviewed on Oct 20, 2023

Dr. Tsai is a very caring and compassionate person...she takes the time to talk to you and is genuinely Interested In one's health... I am blessed to have her as my doctor!

Reviewed on Oct 20, 2023

Dr Tsai was wonderful. She was courteous, caring, knowledgeable, and concerned about my health issues.

Reviewed on Oct 16, 2023

I love this clinic. Everyone is so nice and respectful. Doctor is one of the best understanding doctors I have ever had. I tell everyone about her.

Reviewed on Oct 13, 2023

She is One of the nicest and friendliest.People persons persons that I know.

Reviewed on Oct 13, 2023

Her and her staff are always amazing friendly and they get started at 6:30 ! It appears to Me that Dr.Thai that it'sa nice working for her as it is being treated by her!

Reviewed on Oct 6, 2023

Dr Tsai is truly a one of a kind doctor. She listens to what is said and cares about her patients. I feel blessed she is my doctor.

Reviewed on Oct 6, 2023

I was very impressed with Dr. Tsai. She listened to me describe where I'm having pain. ! She was very thorough and asked me questions I've never been asked before. Great doctor!!!! So glad she was recommended to me!

Reviewed on Oct 6, 2023

Very satisfied with the staff and Doctors care

Reviewed on Oct 6, 2023

Dr tsai is very caring and also shows that she loves and really cares about her patients

Reviewed on Sep 26, 2023

Dr Tsai is extremely caring, knowledgeable, and supportive.

Reviewed on Sep 26, 2023

I feel extremely fortunate to be under Dr. Tsai's care!

Reviewed on Sep 26, 2023

Dr. Tsai was absolutely wonderful. She made sure she took the time to explain everything to me and answer all my questions. She was very compassionate and kind.

Reviewed on Sep 26, 2023

She took the time to explain everything to me and answer all my questions and concerns. She was very compassionate and kind.

Reviewed on Sep 14, 2023

Dr Tsai listens to my concerns and answers all my questions. I would recommend her to anyone.

Reviewed on Sep 7, 2023

Dr Tsai and her staff are amazingly kind, empathic, and sweet to their patients

Reviewed on Sep 5, 2023

Anytime I see Dr.Tsai, it is always a wonderful experience. She really cares for her patients.

Reviewed on Sep 5, 2023

Excellent doctor with great people skills. Caring and compassionate and a good doctor.

Reviewed on Aug 29, 2023

As always, Dr. Tsai is comoassionate, knowledgable and acjoy to talk to

Reviewed on Aug 28, 2023

Dr. Tsai is one of the best doctors I have had. She is so friendly and caring and the concern she shows for me as a patient is genuine.

Reviewed on Aug 22, 2023

Dr. Tsai is the BEST!

Reviewed on Aug 21, 2023

Dr Tsai is very nice and explains things thoroughly

Reviewed on Aug 18, 2023

Dr. Tsai was very thorough and took the time to explain everything to me. I wish she was a primary care survivor - she was amazing!

Reviewed on Aug 18, 2023

Great Doctor

Reviewed on Aug 18, 2023

Dr. Tsai is a wonderful doctor. She takes the time to really listen and cares.

Reviewed on Aug 17, 2023

Dr. Tsai is an amazing physician. She listens, explains and empathizes with your situation. I love her!!

Reviewed on Aug 14, 2023

This doctor is my favorite at the Cleveland Clinic. Listens, very caring, compassionate, works to find the cause of you symptoms more so than any other physician.

Reviewed on Aug 14, 2023

Very personable. A great listener and empathetic to my concerns. I have such great confidence in her and in her abilities.

Reviewed on Aug 14, 2023

She's a very kind and knowledgeable physician who explains details in an easy to understand manner. I'm confident in her advise and my plan of care

Reviewed on Aug 11, 2023

Dr. Tsai is a caring and kind physician; I trust and like her. She is what a patient wants from a doctor.

Reviewed on Aug 7, 2023

Dr. Tsai is compassionate and professional and knowledgeable about the detail of my illness. She remembers what I have stated in the past and applies it to what my treatment plan needs to be. She reviews all my details before she walks into the examination room.

Reviewed on Jul 31, 2023

Dr Tsai is the BEST

Reviewed on Jul 31, 2023

Love Dr Tsai

Reviewed on Jul 31, 2023

I love Dr tsia all my other Dr are through another hospital but I looked for the best rheumatologist near me and I chose her best decision I ever made

Reviewed on Jul 25, 2023

Jenna & Dr TSAI are the BEST!!!!

Reviewed on Jul 25, 2023

Dr. Thai is an excellent communicator and takes a lot of time to listen to my concerns and answer questions. She explains all the pros and cons of conditions, medication, etc.

Reviewed on Jul 24, 2023

I was really impressed with Dr. Tsai. She really listened to my situation and developed a plan around my concerns. She was empthatic and thoughtful. The follow-up through messages on mychart was quick to be answered. Overall a wonderful Doctor and I would recommend her to anyone.

Reviewed on Jul 24, 2023

Dr. Tsai responded within 24 hours of me sending her a message requesting blood work. She did it right away and I appreciated it.

Reviewed on Jul 24, 2023

Dr. Tsai is one of the sweetest Doctors that I have ever come in contact with. Absolutely love her. She is so knowledgeable and spends a lot of time with her patients.

Reviewed on Jul 10, 2023

Dr Tsai was very easy to talk to about my concerns.

Reviewed on Jul 7, 2023

Dr. Tsai cares about me and works to find solutions to my problems. I appreciate the hug at the beginning and end of my visit.

Reviewed on Jul 6, 2023

Dr Tsai is excellent and cares about my treatment and always listens and explains the course of treatment.

Reviewed on Jul 6, 2023

Excellent service from entire staff and physician.

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