Thaddeus Stappenbeck, MD, PhD
Cleveland Clinic Main Campus
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About Thaddeus Stappenbeck, MD, PhD
Thaddeus Stappenbeck received his B.A. as a member of the Integrated Science Program at Northwestern University, as well as his M.D and Ph.D. from Northwestern University Medical School. He trained in anatomic pathology at the Washington University School of Medicine. He was hired as an assistant Professor in the Department of Pathology and Immunology at Washington University, where he moved up the ranks to Division Chief of Laboratory and Genomic Medicine. His leadership experiences included lead of the Physician Scientist Training Program, Pathology and Immunology promotions committee chair, study section chair and multiple search committees for leadership positions.
Dr. Stappenbeck currently serves as the chair of Inflammation and Immunity at Cleveland Clinic, where his research program focuses on determining the root causes of inflammatory and infectious diseases with the goal of developing new therapies for these diseases. His lab has defined stages and mechanisms of intestinal repair leading to a lead compound for a novel therapy for inflammatory bowel disease and idiopathic pulmonary fibrosis, determined mechanisms for the effects of intestinal microbes on repair and created a cell culture system for human intestinal stem cells that is used by labs around the world. He moved to Cleveland Clinic to partner with the world-class clinicians and scientists in this institution to accelerate the translation of discoveries in immunology, developmental biology, cell biology, and microbiology to new concepts for therapy in inflammatory disease.
He serves on scientific advisory boards for Science Immunology, as well as several companies in the area of inflammatory bowel diseases. He has collaborated extensively with many other investigators and published over 160 articles in high impact journals, while successfully training numerous physician-scientists and scientists and encouraging them to inflammatory and infectious disease. His lab has been supported by broad portfolio including the National Institute of Health, Crohn’s Colitis Foundation of America, Helmsley Trust, American Asthma Foundation, Rainin Foundation, Broad Medical Research Program, the Gates Foundation, the Pew Foundation and pharmaceutical companies including Genentech, Pfizer, Janssen and Boehringer-Ingelheim.
Education & Professional Highlights
Education & Fellowships
Fellowship - Washington University in St. Louis
Residency - Barnes Jewish Hospital
St. Louis, MO USA
Medical Education - Northwestern Univ. School of Medicine
Chicago, IL USA
Graduate School - Northwestern Univ. School of Medicine
Chicago, IL USA
Undergraduate - Northwestern University
Integrated Science Program
Evanston, IL USA
- Pathology - Anatomic Pathology
Awards & Honors
Innovations & Patents
Research & Publications
See publications for Thaddeus Stappenbeck, MD, PhD.
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As of 2/1/2022, Dr. Stappenbeck has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.
Consulting and/or Speaking. Dr. Stappenbeck receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:
- Johnson & Johnson
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.