Iobenguane I 123 Injection

What is this medication?

IOBENGUANE I 123 (eye oh BEN gwane) helps find or diagnose pheochromocytoma, a tumor in the adrenal glands. It may also help find or diagnose neuroblastoma, a cancer that occurs in nerve cells. It can be used to assess heart function in heart failure. It works by making cells and tissue easier to view on imaging scans.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): AdreView I-123

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Kidney disease
• An unusual or allergic reaction to iobenguane I 123, iodine, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

How should I use this medication?

This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. While it may be given to children as young as 1 month for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

• Certain medications for blood pressure, such as labetalol or reserpine
• Certain medications for depression, such as amitriptyline
• Decongestants, such as pseudoephedrine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

Talk to your care team about how to prepare for your treatment. It is important to increase the amount of fluids you drink before you receive this medication. Void often for 48 hours after treatment. This will help reduce radiation exposure to your bladder.

Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy.

Do not breastfeed for at least 6 days after your treatment.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Increase in blood pressure

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Dizziness
• Flushing
• Headache
• Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is only given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.