Glycopyrrolate Injection

What is this medication?

GLYCOPYRROLATE (GLY koe PYE roe late) is used during surgery to help your breathing and heart rate stay steady and dry up extra saliva or mucus. It may also be used to treat stomach ulcers.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): GLYRX-PF, Robinul

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Glaucoma
• Heart disease
• Hernia
• Kidney disease
• Liver disease
• Myasthenia gravis
• Stomach or intestine problems, such as a bowel blockage or ulcerative colitis
• Trouble passing urine
• An unusual or allergic reaction to glycopyrrolate, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

How should I use this medication?

This medication is injected into a vein or muscle. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. While it may be given to children for selected conditions, precautions do apply.

People 65 years and older may have a stronger reaction and need a smaller dose.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

• Amantadine
• Antihistamines for allergy, cough, and cold
• Atropine
• Phenothiazines, such as chlorpromazine, prochlorperazine, thioridazine
• Potassium chloride
• Some medications for depression, such as amitriptyline, clomipramine, desipramine
• Some medications for Parkinson disease, such as benztropine or trihexyphenidyl
• Some medications for stomach problems, such as dicyclomine or hyoscyamine
• Some medications for travel sickness, such as scopolamine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells.

This medication can make your eyes more sensitive to the sun. Wear dark sunglasses after your procedure to protect your eyes.

Avoid extreme heat and strenuous exercise after receiving this medication. This medication can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Bowel blockage—stomach cramping, unable to have a bowel movement or pass gas, loss of appetite, vomiting
• Fever that does not go away, decreased sweating
• Heart palpitations—rapid, pounding, or irregular heartbeat
• Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
• Trouble passing urine

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Blurry vision
• Constipation
• Dizziness
• Drowsiness
• Dry mouth
• Sensitivity to light

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.