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Isoproterenol injection

Isoproterenol is a medication that increases the strength of your heart muscle to treat heart failure. This condition occurs when your heart doesn’t pump very well. A healthcare provider will give you this medication as an infusion into your vein in a hospital or clinic.

What is this medication?

ISOPROTERENOL (eye soe proe TER e nole) is an inotrope.It helps increase the strength of the heart muscle. It is used to treat heart failure and heartbeat problems.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Isuprel

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • diabetes
  • heart disease
  • history of irregular heartbeat
  • thyroid disease
  • an unusual or allergic reaction to isoproterenol, other medicines, foods, dyes or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is for injection or infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician about the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medicine is not for regular use.

What may interact with this medication?

Do not take the medicine with any of the following medications:

  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
  • MAOIs like Marplan, Nardil, and Parnate

This medicine may also interact with the following medications:

  • epinephrine
  • general anesthetics like halothane, isoflurane

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives; swelling of the face, lips, or tongue
  • signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast, irregular heartbeat; palpitations; feeling faint or lightheaded; falls; breathing problems

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • dizziness
  • headache
  • facial flushing
  • nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This drug is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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