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Isoproterenol Injection

Isoproterenol is a medication that increases the strength of your heart muscle to treat heart failure. This condition occurs when your heart doesn’t pump very well. A healthcare provider will give you this medication as an infusion into your vein in a hospital or clinic.

What is this medication?

ISOPROTERENOL (eye soe proe TER e nole) treats heart conditions such as slow heartbeat and heart block. It works by helping your heart beat stronger, making it easier for your heart to pump blood to the rest of the body.  It may also be used to treat trouble breathing or wheezing (bronchospasm). It works by opening the airways of the lungs, making it easier to breathe.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Isuprel

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Irregular heartbeat or rhythm
  • An unusual or allergic reaction to isoproterenol, other medications, foods, dyes or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

How should I use this medication?

This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

Do not take this medication with any of the following:

  • Ergot alkaloids, such as dihydroergotamine, ergotamine, methylergonovine
  • MAOIs, such as Marplan, Nardil, and Parnate

This medication may also interact with the following:

  • Epinephrine
  • Medications that cause drowsiness before a procedure

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Blurry vision
  • Dizziness
  • Headache
  • Nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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