Dasiglucagon Injection

What is this medication?

DASIGLUCAGON (DAS i GLU ka gon) treats very low blood sugar (severe hypoglycemia) in an emergency. Call emergency services after using this medication. You may need additional treatment. Dasiglucagon works by helping your liver release stored sugar into your blood, which raises your blood sugar (glucose) levels.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): ZEGALOGUE

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Eating less due to illness, surgery, dieting, or any other reason
• Low adrenal gland function
• Pancreatic tumor
• Pheochromocytoma
• Poor nutrition
• An unusual or allergic reaction to dasiglucagon, latex, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

This medication is for injection under the skin. You will be taught how to prepare and give it. Use exactly as directed.

It is important that you put your used injectors, needles, and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.

This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 6 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medicine is not for regular use.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Always get immediate medical help after receiving an injection of this medication. This is very important. Do this even if you respond to the medication and are alert.

Keep this kit with you at all times. Wear a medical identification bracelet or chain to say you have diabetes, and carry a card that lists all your medications.

Show your family members and others where you keep this kit. Make sure that you and your family or caregiver know how to use this kit the right way before you need it. They need to know how to use it before you need it.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once. Also, remind others that they may need to give you this medication injection before medical help is available. A repeat injection may be needed while waiting for medical help.

After you are alert and can swallow after an injection of this medication, you should eat or drink some carbohydrates to prevent continued low blood sugar.

Do not drive or operate machinery until you are alert and have eaten sugar or a sugar-sweetened product such as a regular soft drink or fruit juice.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Headache
• Nausea
• Pain, redness, or irritation at injection site
• Vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store this medication in the original container until you are ready to take it. Store unopened in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Protect from light. Get rid of any refrigerated, unused medication after the expiration date on the label.

You may store this medication unopened at room temperature between 20 and 25 degrees C (68 and 77 degrees F) for up to 12 months. Protect from light. Do not return to the refrigerator after storing at room temperature. Get rid of any medication that has been stored at room temperature for more than 12 months.

Always replace your medication before it expires. Replace any used medication right away so you will have new medication in case you need it.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.