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Oxymetazoline ophthalmic solution (Blepharoptosis)

What is this medication?

Oxymetazoline (OX ee me TAZ oh leen) tightens the muscles in the eyelid. This medicine is used to treat droopy eyelids.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Upneeq, Visine L.R.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • diabetes
  • glaucoma
  • heart disease
  • high or low blood pressure
  • history of stroke
  • Raynaud's phenomenon
  • scleroderma
  • Sjogren's syndrome
  • thromboangiitis obliterans
  • thyroid disease
  • trouble urinating due to an enlarged prostate gland
  • an unusual or allergic reaction to oxymetazoline, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the container to your eye, fingertips, or any other surface. Squeeze the prescribed number of drops into the pouch. Close the eye for a few moments to spread the drops. Do not use your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

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NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

This medicine may interact with the following medications:

  • MAOIs like isocarboxazid, phenelzine, rasagiline, selegiline, and tranylcypromine
  • medicines to treat blood pressure and heart disease like ace-inhibitors, beta-blockers, calcium-channel blockers, digoxin, and diuretics
  • medicines to treat enlarged prostate like alfuzosin, doxazosin, prazosin, and terazosin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Tell your doctor or health care professional right away if you have any change in your vision.

To prevent the spread of infection, do not share eye products with anyone else.

If you wear contact lenses, ask your doctor or health care professional when you can use your lenses again.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • changes in vision
  • dry eyes
  • eye pain
  • eye irritation
  • headache

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep this medicine in the original container. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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