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Ethiodized Oil Injection

What is this medication?

ETHIODIZED OIL (eth EYE oh dyzd oyl) helps find or diagnose problems with blood vessels, organs, or other tissues in the body. It works by making parts of the body easier to view during imaging scans, such as CT, MRI, or X-ray. It belongs to a group of medications called contrast agents.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Lipiodol

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Cancer
  • Heart disease
  • Kidney disease
  • Liver disease
  • Lung or breathing disease, such as asthma
  • Recent or ongoing radiation
  • Severe injury to your body from trauma, such as a car accident or burn
  • Thyroid disease
  • An unusual or allergic reaction to ethiodized oil, iodine, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

How should I use this medication?

This medication is injected into the uterus, a lymph vessel, or blood vessel in your liver. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. While it may be used for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medication is not for regular use.

What may interact with this medication?

  • Sodium iodide I-131

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

After your procedure, follow the instructions given to you by your care team.

Talk to your care team if you may be pregnant. You may need a pregnancy test before you receive this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
  • High thyroid levels (hyperthyroidism)—fast or irregular heartbeat, weight loss, excessive sweating or sensitivity to heat, tremors or shaking, anxiety, nervousness, irregular menstrual cycle or spotting
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Low thyroid levels (hypothyroidism)—unusual weakness or fatigue, increased sensitivity to cold, constipation, hair loss, dry skin, weight gain, feelings of depression

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Nausea
  • Stomach pain
  • Vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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