Triptorelin Extended-Release Injection (Precocious Puberty)

What is this medication?

TRIPTORELIN (TRIP toe REH lin) treats children with early onset of puberty.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Triptodur

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Brain cancer or tumor
• Mental health disease
• Seizures
• An unusual or allergic reaction to triptorelin, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

This medication is for injection into a muscle. It is given in a hospital or clinic.

A special MedGuide will be given to you before each treatment. Be sure to read this information carefully each time.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 2 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

What may interact with this medication?

• Certain medications for depression, anxiety, or psychotic disturbances
• Methyldopa
• Metoclopramide
• Phenothiazines like chlorpromazine, prochlorperazine
• Reserpine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully. You may need blood work done while taking this medication.

Contact your care team right away if you notice any change in emotions or behaviors such as crying, irritability, restlessness, anger, or acting aggressive while taking this medication.

In the first 2 months of receiving this medication, you may notice more signs of puberty, including vaginal bleeding. If this continues, contact your care team.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Changes in emotions or moods
• Infection—fever, chills, cough, sore throat, pain or trouble passing urine
• Seizures

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Headache
• Hot flashes
• Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.