Lidocaine; Tetracaine Cream

What is this medication?

LIDOCAINE; TETRACAINE (LYE doe kane; TET ra kane) prevents pain during a procedure. It numbs the area where it is applied, which blocks your nerves from sending pain signals to your brain. It belongs to a group of medications called local anesthetics.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Pliaglis

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• G6PD deficiency
• Heart disease
• Kidney disease
• Liver disease
• Pseudocholinesterase deficiency
• Skin conditions or sensitivity
• An unusual reaction to lidocaine, tetracaine, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

How should I use this medication?

This medication is for external use only. It is usually given by your care team to numb the skin before a procedure. Your care team will tell you how long to leave the cream on your skin. Ask your care team if you have questions.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

• Acetaminophen
• Certain antibiotics, such as dapsone, nitrofurantoin, aminosalicylic acid, sulfasalazine
• Certain medications for seizures, such as phenobarbital, phenytoin, valproic acid
• Chloroquine
• Cyclophosphamide
• Flutamide
• Hydroxyurea
• Ifosfamide
• Metoclopramide
• Nitroglycerin
• Other local anesthetics, such as pramoxine
• Primaquine
• Quinine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Avoid contact of the medication with eyes due to severe irritation. If eye contact occurs, wash the eye out with plenty of cool tap water, and protect the eye until feeling returns.

If irritation or burning feelings occur while using the medication, tell your care team.

Be careful to avoid injury while the skin is numb from the medication, and you are not aware of pain. Do not scratch, rub, or expose the skin to hot or cold until sensation returns.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Headache, unusual weakness or fatigue, shortness of breath, nausea, vomiting, rapid heartbeat, blue skin or lips, which may be signs of methemoglobinemia
• Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Change in skin color
• Irritation at application site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is only given by your care team. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.