Finerenone Oral Tablets

What is this medication?

FINERENONE (fin ER e none) is a medicine used to treat people with kidney disease and type 2 diabetes. It may lower the risk for worsened kidney function. It may also lower the risk for a heart attack, the need to be treated in the hospital for heart failure, or death due to heart disease.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Kerendia

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• diet low in salt and are using dietary salt substitutes
• high levels of potassium in the blood
• kidney disease
• liver disease
• low adrenal gland function
• an unusual or allergic reaction to finerenone, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medication?

Take this medicine by mouth with water. Take it as directed on the prescription label at the same time every day. You can take it with or without food. If it upsets your stomach, take it with food. Swallow the tablets whole. You may crush the tablet and put the contents in a small amount of water or soft foods such as applesauce. Swallow the medicine mixture right away. Keep taking it unless your health care provider tells you to stop.

Do not take this medicine with grapefruit or grapefruit juice.

Talk to your health care provider about the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medicine with any of the following medications:

• ceritinib
• certain antivirals for HIV or hepatitis like atazanavir, cobicistat, darunavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir
• certain medicines for fungal infections like itraconazole, ketoconazole, posaconazole, or voriconazole
• chloramphenicol
• clarithromycin
• grapefruit and grapefruit juice
• idelalisib
• lonafarnib
• mifepristone
• nefazodone
• ribociclib
• telithromycin
• tucatinib

This medicine may also interact with the following medicines:

• amiodarone
• certain diuretics like amiloride, spironolactone, and triamterene
• certain medicines for high blood pressure like enalapril, candesartan, lisinopril, and valsartan
• certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
• efavirenz
• erythromycin
• potassium salts or supplements
• rifampin
• St. John's wort

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your health care provider for regular checks on your progress. You may need blood work done while you are taking this medicine.

Avoid salt substitutes unless you are told otherwise by your health care provider.

Do not breast-feed an infant while taking this medicine or for 1 day after stopping treatment.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
• high potassium levels (chest pain; fast, irregular heartbeat; muscle weakness)
• low blood pressure (dizziness; feeling faint or lightheaded, falls; unusually weak or tired)

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

• diarrhea
• fatigue
• headache
• nausea, vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medicine after the expiration date.

To get rid of medicines that are no longer needed or have expired:

• Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put into the trash, take the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.