Methacholine Nebulizer Solution

What is this medication?

METHACHOLINE (meth uh KOH leen) helps diagnose asthma. It is used in a challenge test performed to assess how reactive your lungs are. It works by helping your care team evaluate your symptoms.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Provocholine

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Aneurysm
• Heart disease
• High blood pressure
• History of heart attack
• History of stroke
• Lung or breathing disease
• Seizures
• Stomach or intestine problems
• Thyroid disease
• Trouble passing urine
• An unusual or allergic reaction to methacholine, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

How should I use this medication?

This medication is for inhalation using a nebulizer. Nebulizers make a liquid into an aerosol that you breathe in through your mouth or your mouth and nose and into your lungs. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. While it may be given to children as young as 5 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

• Albuterol
• Beta blockers, such as metoprolol or propranolol
• Inhaled steroids, such as fluticasone
• Ipratropium
• Salmeterol
• Steroid medications, such as prednisone or cortisone
• Theophylline
• Tiotropium

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Wheezing or trouble breathing

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Dizziness
• Headache
• Irritation in the throat
• Itching

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.