Cenegermin Ophthalmic Solution

What is this medication?

CENEGERMIN (sEn Jur min) is used on the eye to treat neurotrophic keratitis.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): OXERVATE

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• infection in the eye
• wear contact lenses
• an unusual or allergic reaction to cenegermin, medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medication?

This medicine is only for use in the eye. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper to your eye, fingertips, or any other surface. Squeeze the drop into the pouch. Blink for a few moments to spread the drops. Use exactly as directed. Use your doses at regular intervals. Do not use your medicine more often than directed.

Talk to your pediatrician regarding use of this medicine in children. While this drug may be prescribed for children as young as 2 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use the next dose at your regular time. Do not use double or extra doses.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your doctor or health care professional for regular eye exams. Ask your doctor or health care professional if you should continue to use this medicine if you injure your eyes or need eye surgery. If you develop an eye infection, contact your doctor or health care professional immediately.

If you wear contact lenses, you should not put this medicine in your eyes while wearing the lenses. After using the eye drops, wait about 15 minutes before putting lenses in your eyes.

You can use other eye medicines while using this medicine; however you should wait at least 15 minutes after using this medicine.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Eye pain

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Eye irritation or itching
• Increased tears after use

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

You will be instructed how to store this medicine.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.