Netarsudil; Latanoprost Eye Solution

What is this medication?

NETARSUDIL; LATANOPROST (ne TAR soo dil; la TA noe prost) treats conditions with increased pressure of the eye, such as glaucoma. It works by decreasing the amount of fluid in the eye, which helps lower eye pressure.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Rocklatan

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Eye injury, infection, or swelling
• Wear contact lenses
• An unusual or allergic reaction to latanoprost, netarsudil, benzalkonium chloride, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

This medication is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Tilt the head back slightly and pull down the lower lid with the index finger to form a pouch. Try not to touch the tip of the dropper to your eye or into the pouch. Squeeze one drop into the pouch. Close the eye gently. Do not blink or rub your eyes. Use your doses at regular intervals. Do not use your medication more often than directed. If you are using another eye product, wait at least 5 minutes between use of this medication and the other eye product.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, continue with the next dose in the evening. Do not take double or extra doses.

What may interact with this medication?

• Bromfenac
• Eye drops that contain thimerosal (a preservative)

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Report any serious side effects right away. Stop using this medication if your eyes get swollen, painful, or have a discharge, and see your care team as soon as you can.

This medication may cause your eye, eyelashes, and eyelids to change color. Tell your care team if this happens. If only one eye is being treated with this medication, a difference may develop between the treated and untreated eye in eyelash length, darkness or thickness, and color changes of the eyelid skin or iris. These changes may be permanent.

If you are using another eye medication, wait at least 5 minutes in between using each medication.

If you wear contact lenses, take them out before using this medication. Wait 15 minutes before putting them back into your eyes.

Wear dark glasses if this medication makes your eyes more sensitive to light.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Change in vision
• New or worsening eye pain, redness, irritation, or discharge

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Blurry vision
• Change in eye, eyelash, or eyelid color
• Eye irritation or itching
• Increase in length, thickness, or number of eyelashes
• Increased tears after use
• Sensitivity to light

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store unopened container in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). After opening, it may be stored between 2 and 25 degrees C (36 to 77 degrees F) for up to 6 weeks. If the open container is kept between 2 and 8 degrees C (36 and 46 degrees F), it can be used until the expiration date on the container. Protect from light.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.