Glycopyrronium topical cloth

What is this medication?

GLYCOPYRRONIUM (glye koe PYE roe nee um) is a topical wipe used to treat underarm sweating.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Qbrexza

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • difficulty passing urine
  • glaucoma
  • heart disease or irregular heartbeat
  • intestinal problems
  • kidney disease
  • myasthenia gravis
  • Sjogren's syndrome
  • stomach obstruction
  • ulcerative colitis
  • an unusual or allergic reaction to glycopyrronium, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is for external use only. Do not take by mouth. Follow the directions on the prescription label. Wash your hands after use. Wipe the cloth under each armpit only once. Do not cover with a bandage or dressing. Do not use on broken skin. Do not get this medicine in your eyes. Do not use your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. While this drug may be prescribed for children as young as 9 years of age for selected conditions, precautions may apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

This does not apply.

What may interact with this medication?

  • atropine
  • antihistamines for allergy, cough and cold
  • certain medicines for bladder problems like oxybutynin, tolterodine
  • certain medicines for stomach problems like dicyclomine, hyoscyamine
  • certain medicines for travel sickness like scopolamine
  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
  • ipratropium

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

You may have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you.

Avoid extreme heat (e.g., hot tubs, saunas). This medicine can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • irregular heartbeat
  • pain or difficulty passing urine

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • blurred vision and other eye problems
  • constipation
  • dry mouth
  • headache

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

This medicine is flammable. Avoid exposure to heat, fire, flame, or smoking.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

Terms of use.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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