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Sodium Phosphate Injection

What is this medication?

SODIUM PHOSPHATE (SOE dee um FOS fate) prevents and treats low phosphorus levels in your body. Phosphorus is a mineral that plays an important role in maintaining the health of your bones, muscles, digestive tract, and nervous system.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Heart disease
  • High blood pressure
  • High levels of sodium or phosphorus in the blood
  • Kidney disease
  • Low salt or sodium diet
  • An unusual or allergic reaction to sodium, phosphorus, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

This medication is for infusion into a vein. It is given in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

Do not take this medication with any of the following:

  • Sevelamer

This medication may also interact with the following:

  • Certain medications for blood pressure like diazoxide, guanethidine, hydralazine, methyldopa
  • Other sodium or phosphorus supplements
  • Steroid medications like cortisone, fludrocortisone

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

You may need blood work done while receiving this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • High phosphorus level—muscle pain or cramps, bone or joint pain, numbness and tingling around the mouth
  • High sodium level—confusion, increased thirst, muscle weakness, unusual weakness or fatigue, twitching muscles

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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