Angiotensin II injection

Antigiotensin II injections are a treatment option for people with low blood pressure. Healthcare providers give antigiotensin II through an injection in your vein. The medicine works by constricting your blood vessels, making them narrower. This helps raise your blood pressure.

What is this medication?

ANGIOTENSIN II (an jee oh TEN sin too) is a vasoconstrictor. This medicine is used in a hospital to treat low blood pressure.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): GIAPREZA

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • an unusual or allergic reaction to angiotensin II, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

This does not apply.

What may interact with this medication?

This medicine may interact with the following medications:

  • certain medicines for blood pressure or heart disease like benazepril, candesartan, enalapril, irbesartan, lisinopril, losartan, ramipril, and valsartan

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • signs and symptoms of a blood clot such as breathing problems; changes in vision; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm, or leg
  • signs and symptoms of high blood sugar such as dizziness; dry mouth; dry skin; fruity breath; nausea; stomach pain; increased hunger or thirst; increased urination
  • signs and symptoms of increased acid in the body like breathing fast; fast heartbeat; headache; confusion; feeling weak or tired; nausea, vomiting
  • unusual bleeding or bruising

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This drug is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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