Testosterone Subcutaneous Injection
What is this medication?
TESTOSTERONE (tes TOS ter one) is used to increase testosterone levels in your body. It belongs to a group of medications called androgen hormones.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): XYOSTED
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Heart disease
- High blood pressure
- Kidney disease
- Liver disease
- Lung disease
- Prostate disease
- Suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
- An unusual or allergic reaction to testosterone, sesame oil, other medications, foods, dyes, or preservatives
- If a female partner is pregnant or trying to get pregnant
How should I use this medication?
This medication is for injection under the skin. You will be taught how to prepare and give this medication. Use exactly as directed. Take your medication at regular intervals. Do not take your medication more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
It is important that you put your used injectors in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. Call your care team if you are not sure how to handle a missed dose.
What may interact with this medication?
- Certain medications for colds or congestion, like ephedrine, phenylephrine, or pseudoephedrine
- Certain medications that treat or prevent blood clots like warfarin
- Medications for diabetes
- Steroid medications like prednisone or cortisone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. They will need to check the level of testosterone in your blood.
This medication is only approved for use in men who have low levels of testosterone related to certain medical conditions. Heart attacks and strokes have been reported with the use of this medication. Notify your care team and seek emergency treatment if you develop breathing problems; changes in vision; confusion; chest pain or chest tightness; sudden arm pain; severe, sudden headache; trouble speaking or understanding; sudden numbness or weakness of the face, arm or leg; loss of balance or coordination. Talk to your care team about the risks and benefits of this medication.
This medication may affect blood sugar levels. If you have diabetes, check with your care team before you change your diet or the dose of your diabetic medication.
Testosterone injections are not commonly used in women. Women should inform their care team if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your care team or pharmacist for more information. Talk with your care team about your birth control options while taking this medication.
This medication is banned from use in athletes by most athletic organizations.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching or hives, swelling of the face, lips, tongue, or throat
- Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
- Heart attack—pain or tightness in the chest, shoulders, arm, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
- Increase in blood pressure
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Mood swings, irritability, or hostility
- Prolonged or painful erection
- Sleep apnea—loud snoring, gasping during sleep, daytime sleepiness
- Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
- Swelling of the ankle, hands, or feet
- Thoughts of suicide or self-harm, worsening mood, feelings of depression
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Change in sex drive or performance
- Pain, redness, or irritation at the application site
- Unexpected breast tissue growth
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store between 15 and 30 degrees C (59 and 86 degrees F). Keep this medication in the original container until time of use. Do not refrigerate or freeze. Protect from light. Throw away any unused medication after the expiration date on the label.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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