Locations:

Hydrogen Peroxide Topical Solution (Seborrheic Keratosis)

Hydrogen peroxide solution treats raised skin growths. A healthcare provider will give this solution to you. It’s for external use only. Report any side effects, like skin irritation, to your provider.

What is this medication?

HYDROGEN PEROXIDE (HY druh juhn puh ROK syd) treats seborrheic keratosis, a condition that causes raised dark spots on the skin.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): CLEAR CARE PLUS with HydraGlyde, Proxacol

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Have had other treatments for seborrheic keratosis
  • Other skin conditions
  • An unusual or allergic reaction to hydrogen peroxide, other medications, foods, dyes or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

This medication is for external use only. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

Interactions are not expected. Do not use any other skin products on the same area of skin without talking to your care team.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Advertisement

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication. Another treatment may be needed.

This medication can cause severe eye injury during application. Tell your care team if this medication gets into your eyes, mouth, or nose during application. If it gets into your eyes, flush both eyes with water for 15 to 30 minutes. Your care team may send you for further treatment if needed.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Burning, itching, crusting, or peeling of treated skin
  • Mild skin irritation, redness, or dryness

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Advertisement

Copyright ©2025 Elsevier Inc. All Rights Reserved.

Terms of use.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

Ad