Dutasteride Capsules

What is this medication?

DUTASTERIDE (doo TAS teer ide) treats the symptoms of an enlarged prostate (benign prostatic hyperplasia). It works by decreasing the size of the prostate. It belongs to a group of medications called 5-alpha reductase inhibitors.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Avodart

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Liver disease
• Prostate cancer
• An unusual or allergic reaction to dutasteride, finasteride, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, chew, or open this medication. Swallow the capsules whole. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

• Boceprevir
• Certain antivirals for HIV
• Certain medications for fungal infections, such as ketoconazole, itraconazole, or voriconazole
• Certain medications for infection, such as erythromycin or telithromycin
• Cimetidine
• Diltiazem
• Supplements, such as saw palmetto
• Verapamil

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication.

This medication can cause serious birth defects. If you are pregnant or may get pregnant, do not handle this medication. If you are pregnant and come into contact with a broken, crushed, or leaking capsule, immediately wash the exposed area of skin with soap and water and contact your care team.

Do not donate blood while you are taking this medication or for 6 months after stopping it. Donated blood may contain enough of this medication to cause serious birth defects in someone who is pregnant.

This medication can interfere with PSA laboratory tests for prostate cancer. If you are scheduled to have a blood test for prostate cancer, tell your care team that you are taking this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Breast tissue changes, new lumps, redness, pain, or discharge from the nipple

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Breast pain or tenderness
• Change in sex drive or performance

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep the container tightly closed. Avoid exposure to extreme heat. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.