Locations:

Niacin Extended-Release Capsules or Tablets

What is this medication?

NIACIN (NYE a sin) prevents and treats low niacin levels in your body. Niacin (vitamin B3) plays an important role in maintaining the health of your heart, blood vessels, and metabolism. It may also be used with other medications to decrease bad cholesterol and fats (such as LDL, triglycerides) and increase good cholesterol (HDL) in your blood.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): ENDUR-AMIDE, Niaspan, NiaVasc, Slo-Niacin

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Bleeding problems
  • Frequently drink alcohol
  • Liver disease
  • Ulcers of intestine or stomach
  • An unusual or allergic reaction to niacin, other medications, foods, dyes, or preservatives
  • Pregnant or trying or get pregnant
  • breast-feeding

How should I use this medication?

Take this medication by mouth with water. Take it as directed on the label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. Take it with a low-fat meal or snack. Keep taking it unless your care team tells you to stop.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

Advertisement

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

  • Aspirin
  • Medications for blood pressure, chest pain, or heart disease
  • Nitroglycerin
  • Nutritional supplements that contain niacin or nicotinamide
  • Other medications to lower cholesterol or triglycerides

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Advertisement

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. You may need blood work while you are taking this medication.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

Do not drink hot drinks or alcohol at the same time you take this medication. Hot drinks and alcohol can increase the flushing caused by this medication, which can be uncomfortable.

Taking this medication is only part of a total heart healthy program. Ask your care team if there are other changes you can make to improve your overall health.

If you have diabetes, close monitoring of your blood sugar can help your blood fat levels. This medication may change the way your diabetes medication works. Your dosage might need to be adjusted. Check with your care team.

The tablet shell of this medication does not dissolve. This is normal. The tablet shell may appear whole in the stool This is not a cause for concern.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Bloating
  • Burping
  • Facial flushing, redness
  • Gas

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

Terms of use.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

Ad
Call Appointment Center 866.320.4573
Questions 216.444.2200