Methylene blue is a medication that treats methemoglobinemia. This is a rare blood condition that affects how red blood cells deliver oxygen throughout your body. A healthcare provider will give you this injection in a hospital or a clinic setting. The brand name of this medication is Provayblue®.
METHYLENE BLUE (METH uh leen bloo) is used to treat methemoglobinemia. This is a condition in which the blood loses its ability to carry oxygen through the body.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): PROVAYBLUE
They need to know if you have any of these conditions:
•glucose-6-phosphate dehydrogenase (G6PD) deficiency
•an unusual or allergic reaction to methylene blue, phenothiazines, thiazide diuretics, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
This does not apply.
Do not take this medicine with any of the following medications:
•certain medicines for depression or anxiety
•MAOIs like Marplan, Nardil, and Parnate
•St. John's wort
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Your condition will be monitored carefully while you are receiving this medicine.
Side effects that you should report to your doctor or health care professional as soon as possible:
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
•blue-green coloration of urine and stools
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
This drug is given in a hospital or clinic and will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.