Leflunomide is a medication that treats rheumatoid arthritis. Rheumatoid arthritis occurs when your immune system attacks the tissue lining the joints on both sides of your body. The brand name of this medication is Arava®. You can take this medication by mouth with a glass of water as directed.
LEFLUNOMIDE (le FLOO na mide) is for rheumatoid arthritis.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Arava
They need to know if you have any of these conditions:
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your health care provider for regular checks on your progress. Tell your doctor or health care provider if your symptoms do not start to get better or if they get worse. You may need blood work done while you are taking this medicine.
This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
This medicine may stay in your body for up to 2 years after your last dose. Tell your doctor about any unusual side effects or symptoms. A medicine can be given to help lower your blood levels of this medicine more quickly.
Women must use effective birth control with this medicine. There is a potential for serious side effects to an unborn child. Do not become pregnant while taking this medicine. Inform your doctor if you wish to become pregnant. This medicine remains in your blood after you stop taking it. You must continue using effective birth control until the blood levels have been checked and they are low enough. A medicine can be given to help lower your blood levels of this medicine more quickly. Immediately talk to your doctor if you think you may be pregnant. You may need a pregnancy test. Talk to your health care provider or pharmacist for more information.
You should not receive certain vaccines during your treatment and for a certain time after your treatment with this medication ends. Talk to your health care provider for more information.
Side effects that you should report to your doctor or health care professional as soon as possible:
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.