Diphenhydramine phenylephrine is an antihistamine and decongestant. It treats allergies, colds, congestion and other sinus problems. You take this medication by chewing and swallowing it.
DIPHENHYDRAMINE; PHENYLEPHRINE (dye fen HYE dra meen; fen il EF rin) is a combination of an antihistamine and a decongestant. It is used to treat the symptoms of allergies, a cold, or other sinus problems. It may help with congestion and runny nose. This medicine will not treat an infection.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): D-Tann, DiphenMax D, Dytan-D, Uni-Tann D
They need to know if you have any of these conditions:
•high blood pressure
•stomach ulcer or obstruction
•taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate within the last 14 days
•trouble passing urine
•an unusual or allergic reaction to diphenhydramine, phenylephrine, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
Take this medicine by mouth. Chew it completely before swallowing. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of the following medications:
•ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
•MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
•stimulant medicines for attention disorders, weight loss, or to stay awake
This medicine may also interact with the following medications:
•barbiturates like phenobarbital
•medicines for depression, anxiety, or psychotic disturbances
•medicines for sleep
•narcotic medicines for pain
•other medicines for cold, cough, or allergy
•St. John's Wort
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Side effects that you should report to your doctor or health care professional as soon as possible:
•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
•anxiety, nervous, or restless
•changes in blood pressure
•changes in vision
•fast, irregular heartbeat
•problems with balance, talking, or walking
•trouble passing urine or change in the amount of urine
•unusual bleeding or bruising
•unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
•dry eyes or mouth
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep medicine bottle closed tightly. Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.