Norepinephrine injection

Norepinephrine injections treat low blood pressure. They work by narrowing your blood vessels. When blood vessels narrow, it takes more pressure for the blood to travel. This increases blood pressure.

What is this medication?

NOREPINEPHRINE (nor ep ih NEFF rin) is a very strong vasoconstrictor. This medicine is used in a hospital to treat low blood pressure.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Levophed

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • circulation problems in fingers and toes
  • dehydration
  • history of blood clots
  • history of irregular heartbeat
  • an unusual or allergic reaction to norepinephrine, sulfites, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

This does not apply.

What may interact with this medication?

Do not take this medicine with any of the following medications:

  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine

This medicine may also interact with the following medications:

  • certain medicines for depression like amitriptyline
  • general anesthetics like halothane, isoflurane, methoxyflurane
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for diabetes

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • signs and symptoms of increased acid in the body like breathing fast; fast heartbeat; headache; confusion; unusually weak or tired; nausea, vomiting
  • skin discoloration
  • unusually low heartbeat

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • anxious
  • headache

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This drug is given in a hospital and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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