Propranolol; Hydrochlorothiazide, HCTZ Oral Tablet

What is this medication?

PROPRANOLOL; HYDROCHLOROTHIAZIDE (proe PRAN oh lole; hye droe klor oh THYE a zide) is a combination of a beta blocker and a diuretic. It treats high blood pressure.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Inderide

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• circulation problems, or blood vessel disease
• decreased urine
• diabetes
• gout
• heart disease
• immune system problems
• kidney disease
• liver disease
• lung or breathing disease, like asthma
• pheochromocytoma
• thyroid disease
• an unusual or allergic reaction to this propranolol, hydrochlorothiazide, sulfa drugs, other drugs, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medication?

Take this drug by mouth. Take it as directed on the prescription label at the same time every day. Keep taking it unless your health care provider tells you to stop.

Talk to your health care provider about the use of this drug in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

This medicine may also interact with the following medications:

• aluminum hydroxide gel
• antipyrine
• barbiturates like phenobarbital
• chlorpromazine
• cimetidine
• haloperidol
• lidocaine
• lithium
• medicines for diabetes
• medicines that relax muscles for surgery
• NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
• phenytoin
• reserpine
• rifampin
• steroid medicines like prednisone or cortisone
• theophylline
• thyroid medicines

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your doctor or health care professional for regular check-ups. Contact your doctor right away if your symptoms worsen. Check your blood pressure and pulse rate regularly. Ask your health care professional what your blood pressure and pulse rate should be, and when you should contact them.

Do not stop taking this medicine suddenly. This could lead to serious heart-related effects.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.

Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.

Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

Talk to your health care professional about your risk of skin cancer. You may be more at risk for skin cancer if you take this medicine.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
• breathing problems
• changes in vision
• chest pain
• eye pain
• fast or irregular heartbeat
• feeling faint or lightheaded, falls
• gout attack
• muscle pain or cramps
• pain or difficulty when passing urine
• pain, tingling, numbness in the hands or feet
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.
• slow heart rate
• swelling of the legs and ankles
• unusually weak

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• change in sex drive or performance
• diarrhea
• dry mouth
• hair loss
• headache
• stomach upset

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets. Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Keep the container tightly closed. Do not freeze. Avoid exposure to extreme heat. Throw away any unused drug after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.