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Chloroquine Tablets

Chloroquine is a medication that treats and prevents malaria infections. Malaria occurs after mosquitos deposit parasites into your body. You can take this medication by mouth with a glass of water as directed.

What is this medication?

CHLOROQUINE (KLOR oh kwin) prevents and treats malaria. It works by killing the parasite that causes malaria. It may also be used to treat infections caused by other parasites. It will not treat colds, the flu, or infections caused by bacteria or viruses.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Aralen

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Diabetes
  • Eye disease, vision problems
  • Frequently drink alcohol
  • G6PD deficiency
  • Hearing problems
  • Heart disease
  • History of irregular heartbeat
  • Liver disease
  • Porphyria
  • Psoriasis
  • Seizures
  • An unusual or allergic reaction to chloroquine, hydroxychloroquine, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. You can take it with or without food. If it upsets your stomach, take it with food. Take antacids at a different time of day than this medication. Take this medication 4 hours BEFORE or 4 hours AFTER antacids. Take all of this medication unless your care team tells you to stop it early. Keep taking it even if you think you are better.

Talk to your care team about the use of this medication in children. While it may be prescribed for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

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NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medication with any of the following:

  • Cisapride
  • Dronedarone
  • Pimozide
  • Thioridazine

This medication may also interact with the following:

  • Ampicillin
  • Antacids
  • Cimetidine
  • Cyclosporine
  • Kaolin
  • Medications for diabetes, such as insulin, glipizide, glyburide
  • Mefloquine
  • Other medications that cause heart rhythm changes
  • Praziquantel
  • Rabies vaccine
  • Tamoxifen

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

You may need blood work while taking this medication. If you take other medications that can affect heart rhythm, you may need more testing. Talk to your care team if you have questions.

Your vision may be tested before and during use of this medication. Tell your care team right away if you have any change in your eyesight.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Blurry vision, vision loss, seeing wavy or bent objects or blind spots with dark, light, or flashing spots
  • Hearing loss, ringing in ears
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
  • Hemolytic anemia—unusual weakness or fatigue, dizziness, headache, trouble breathing, dark urine, yellowing skin or eyes
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
  • Low blood sugar (hypoglycemia)—tremors or shaking, anxiety, sweating, cold or clammy skin, confusion, dizziness, rapid heartbeat
  • Muscle injury—unusual weakness or fatigue, muscle pain, dark yellow or brown urine, decrease in amount of urine
  • Pain, tingling, or numbness in the hands or feet

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Diarrhea
  • Headache
  • Loss of appetite
  • Nausea
  • Stomach pain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Where should I keep my medication?

Keep out of the reach of children and pets.

Store between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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